Chen Zhi, Chen Jiayun, Pan Dong, Li Hongwei, Yao Yunhui, Lyu Zu, Yang Liting, Ma Li-Jun
School of Chemistry and Environment, South China Normal University, Shipai, Guangzhou, Guangdong, 510631, China.
State Key Laboratory of Supramolecular Structure and Materials, Jilin University, No. 2699, Qianjin Street, Changchun, Jilin, 130012, China.
Anal Bioanal Chem. 2017 Mar;409(9):2429-2435. doi: 10.1007/s00216-017-0189-x. Epub 2017 Jan 26.
A new rhodamine B-based "reactive" optical sensor (1) for Hg was synthesized. Sensor 1 shows a unique colorimetric and fluorescent "turn-on" selectivity to Hg over 14 other metal ions with a hypersensitivity (detection limits are 27.6 nM (5.5 ppb) and 6.9 nM (1.4 ppb), respectively) in neutral buffer solution. To test its applicability in the environment, sensor 1 was applied to quantify and visualize low levels of Hg in tap water and river water samples. The results indicate sensor 1 is a highly sensitive fluorescent sensor for Hg with a detection limit of 1.7 ppb in tap water and river water. Moreover, sensor 1 is a convenient visualizing sensor for low levels of Hg (0.1 ppm) in water environment (from colorless to light pink). In addition, sensor 1 shows good potential as a fluorescent visualizing sensor for Hg in fetal bovine serum and living 293T cells. The results indicate that sensor 1 shows good potential as a highly sensitive sensor for the detection of Hg in environmental and biological samples. Graphical Abstract A new rhodamine B-based "reactive" optical sensor (1) for Hg was synthesized. 1 shows a unique colorimetric and fluorescent "turn-on" selectivity to Hg over 14 other metal ions with a hypersensitivity in water environment. And it is a convenient visualizing probe for low levels of Hg in environment aqueous media, fetal bovine serum and living 293T cells.
合成了一种基于罗丹明B的新型汞“反应性”光学传感器（1）。传感器1对汞显示出独特的比色和荧光“开启”选择性，相对于其他14种金属离子，在中性缓冲溶液中具有超灵敏度（检测限分别为27.6 nM（5.5 ppb）和6.9 nM（1.4 ppb））。为测试其在环境中的适用性，将传感器1应用于定量和可视化自来水和河水样品中的低水平汞。结果表明，传感器1是一种对汞高度敏感的荧光传感器，在自来水和河水中的检测限为1.7 ppb。此外，传感器1是一种用于水环境中低水平汞（0.1 ppm）的便捷可视化传感器（从无色变为浅粉色）。此外，传感器1在胎牛血清和活的293T细胞中作为汞的荧光可视化传感器显示出良好的潜力。结果表明，传感器1作为检测环境和生物样品中汞的高灵敏度传感器具有良好的潜力。图形摘要：合成了一种基于罗丹明B的新型汞“反应性”光学传感器（1）。1在水环境中对汞相对于其他14种金属离子显示出独特的比色和荧光“开启”选择性以及超灵敏度。并且它是用于环境水介质、胎牛血清和活的293T细胞中低水平汞的便捷可视化探针。
