Bossi E, Bossi L
Ospedale Maria Vittoria, Torino.
Minerva Med. 1989 Sep;80(9):991-8.
The effectiveness of a specific treatment for ictus in its acute phase is highly controversial. A series of variables is identified in 1503 cases that would appear to have a particular effect on the reduction of mortality. On these, specific treatment with Buflomedil coincides with a reduction in lethal outcome of 4% over the two-year period out of 380 cases. In their turn chronic postictal and cerebral ischaemia states (a total of 105 cases) respond positively to prolonged treatment with Buflomedil in a percentage varying from 57% in postictal chronic states to 70-73% in chronic cerebral ischemias.
一种针对卒中急性期的特定治疗方法的有效性极具争议。在1503例病例中确定了一系列变量,这些变量似乎对降低死亡率有特殊影响。其中,在380例病例中,使用丁咯地尔进行的特定治疗在两年期间使致命结局降低了4%。反过来,慢性卒中后和脑缺血状态(共105例)对丁咯地尔的长期治疗有积极反应,反应率在卒中后慢性状态中为57%,在慢性脑缺血中为70 - 73%。