Bossi L
Minerva Med. 1985 May 19;76(21):1005-18.
Acute cerebral ischaemia may take considerable advantages of an adequate intensive therapy associated with a specific treatment of cerebral oedemas, especially in terms of mortality-rate reduction. Moreover, target treatment of acute cerebral ischaemia may produce excellent results in severe cases selected by means of EEG-chronospectrography. Double-blind, randomized comparison between nicergolin and buflomedil especialls showed that the latter reduces mortality three times as much as nicergolin, and leads to a 200% increment in the complete recovery of the "functio laesa", limited to those cases, which showed an appreciable improvement following EEG-chronospectrographical survey.
急性脑缺血若能结合针对脑水肿的特效治疗进行充分的强化治疗，可能会带来诸多益处，尤其是在降低死亡率方面。此外，通过脑电图时间频谱图选择的重症急性脑缺血病例，进行靶向治疗可能会产生极佳的效果。尼麦角林和丁咯地尔的双盲随机对照比较特别显示，后者降低死亡率的效果是尼麦角林的三倍，并且在脑电图时间频谱图检查后显示有明显改善的病例中，能使“功能受损”完全恢复的比例提高200%。
