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食物消化过程中的胃混合:机制与应用。

Gastric Mixing During Food Digestion: Mechanisms and Applications.

机构信息

Department of Biological and Agricultural Engineering, University of California, Davis, California 95616; email:

出版信息

Annu Rev Food Sci Technol. 2017 Feb 28;8:523-542. doi: 10.1146/annurev-food-030216-025802. Epub 2017 Jan 23.

DOI:10.1146/annurev-food-030216-025802
PMID:28125347
Abstract

Gastric mixing is a complex process that is governed by meal properties, such as food buffering capacity, physical properties, and the rate of breakdown as well as physiological factors, such as the rate of gastric secretions, gastric emptying, and gastric motility. Gastric mixing processes have been studied through the use of experimental and computational methods. Gastric mixing impacts the intragastric pH distribution and residence time in the stomach for ingested materials. Development of a fundamental understanding of the advective and diffusion processes and their roles in gastric mixing will be important in furthering our understanding of food breakdown, microbial survival, and drug dissolution during gastric digestion.

摘要

胃混合是一个复杂的过程,由进餐性质决定,如食物缓冲能力、物理性质和分解速度以及生理因素,如胃分泌速度、胃排空和胃动力。胃混合过程已经通过使用实验和计算方法进行了研究。胃混合会影响摄入物质在胃内的 pH 值分布和停留时间。深入了解对流和扩散过程及其在胃混合中的作用,对于进一步了解食物分解、微生物存活和药物在胃消化过程中的溶解情况将是重要的。

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