Dedeoglu N, Altun O, Kucuk E B, Altindis S, Hatunogl E
Bratisl Lek Listy. 2016;117(12):691-696. doi: 10.4149/BLL_2016_133.
The aim of this study was to evaluate the frequency of anatomical variation in nasal cavity and paranasal sinuses by comparing a unilateral cleft lip and palate (UCLP) group with a non-syndromic control group using cone beam computed tomography (CBCT).
This study included 24 UCLP patients in the UCLP group and 24 non-syndromic patients in the control group. Coronal CBCT images were taken in all patients and were evaluated for anatomical variation. The measurements obtained in this study were analysed using chi-square and Fisher's exact tests to compare the two groups statistically.
In the UCLP group, there were statistically lower frequencies of pterygoid process pneumatisation (p<0.05), higher wing pneumatisation (p<0.05), and sphenoid sinus over pneumatisation (p<0.05), and statistically higher frequencies of anterior nasal septal deviation (p<0.05) compared to the control group.
A higher incidence of anterior nasal septal deviation was found in UCLP patients compared to the patients in the control group. It is likely that for this reason, UCLP patients might be predisposed to sinusitis. In UCLP patients, the incidence of neurovascular structures in the sphenoid sinus was lower than that in non-syndromic control patients (Tab. 1, Fig. 6, Ref. 33).
本研究旨在通过使用锥形束计算机断层扫描(CBCT),将单侧唇腭裂(UCLP)组与非综合征对照组进行比较,评估鼻腔和鼻窦解剖变异的频率。
本研究纳入UCLP组的24例UCLP患者和对照组的24例非综合征患者。对所有患者进行冠状位CBCT成像,并评估解剖变异情况。本研究获得的测量数据采用卡方检验和费舍尔精确检验进行分析,以对两组进行统计学比较。
与对照组相比,UCLP组翼突气化频率在统计学上较低(p<0.05),翼部气化频率较高(p<0.05),蝶窦过度气化频率较高(p<0.05),前鼻中隔偏曲频率在统计学上较高(p<0.05)。
与对照组患者相比,UCLP患者前鼻中隔偏曲的发生率更高。可能因此,UCLP患者易患鼻窦炎。在UCLP患者中,蝶窦内神经血管结构的发生率低于非综合征对照患者(表1,图6,参考文献33)。