Singh Gurucharan, Singh S J, Chakrabarty N, Siddharaju K S, Prakash J C
Indian J Dermatol Venereol Leprol. 1989 May-Jun;55(3):167-169.
Cutaneous manifestations of chronic renal failure (CRF) were studied in 20 cases. Generalised pruritus was observed in 8 patients, ichthyotic skin changes of varying degree in 18 patients and hyperpigmentation of sun-exposed skin in 7 patients. Scaling, pallor and hair loss correlated strongly with the severity of CRF. Skin biopsy performed in 5 cases revealed mild hyperkeratosis, reduction of prickle cell layer and flattening of rate ridges. No significant dermal changes were detected.
对20例慢性肾衰竭（CRF）患者的皮肤表现进行了研究。8例患者出现全身性瘙痒，18例患者有不同程度的鱼鳞病样皮肤改变，7例患者暴露于阳光下的皮肤出现色素沉着。脱屑、苍白和脱发与CRF的严重程度密切相关。5例患者进行了皮肤活检，结果显示轻度角化过度、棘细胞层减少和嵴变平。未检测到明显的真皮变化。
