Fischer H, Sonnweber N, Berger H
Universitäts-Kinderklinik, Innsbruck.
Padiatr Padol. 1989;24(3):237-44.
There are substantial differences in the family history, the history of pregnancy and delivery and the course in the first week of life of patients with congenital malformations and patients with developmental or intrauterine growth retardation. Patients with malformations demonstrate a high degree of relatives with malformations; in contrast problems in pregnancy, delivery and postnatal development are less pronounced. Mothers of children with intrauterine growth retardation present with a history of early abortion, prematurity, bleeding, toxemia of pregnancy and tobacco abuse. These children present a great number of problems during the first week of life. Patients with mental retardation present with a history of previous abortion prematurity and tobacco and alcohol abuse during pregnancy. These children also present with significant morbidity in the first week of life. The history of these children discloses an unusual number of siblings with death in early life.
先天性畸形患者与发育迟缓或宫内生长迟缓患者在家族史、妊娠和分娩史以及出生后第一周的病程方面存在显著差异。畸形患者的亲属中畸形发生率较高；相比之下，妊娠、分娩及产后发育方面的问题则不太明显。宫内生长迟缓儿童的母亲有早期流产、早产、出血、妊娠中毒症及吸烟史。这些儿童在出生后第一周会出现大量问题。智力发育迟缓患者有既往流产、早产史，其母亲在孕期有吸烟和酗酒史。这些儿童在出生后第一周也有明显的发病率。这些儿童的家族史显示，早年夭折的兄弟姐妹数量异常之多。
