Colin de Verdière Sylvie, Noel Esther, Lozano Claire, Catherinot Emilie, Martin Mickael, Rivaud Elisabeth, Couderc Louis-Jean, Salvator Hélène, Bustamante Jacinta, Martin Thierry
Respiratory Diseases Department, Foch Hospital, Suresnes, France.
Internal Medicine Department, Strasbourg University Hospital, Strasbourg, France.
J Clin Immunol. 2017 Feb;37(2):113-116. doi: 10.1007/s10875-017-0370-1. Epub 2017 Jan 27.
Chronic granulomatous disease (CGD) is a primary immunodeficiency associated to multiple life-threatening bacterial and fungal infections, beginning in childhood. There are rare cases of diagnosis in adulthood. We describe here two cases of late diagnosis in adults: a 45-year-old woman and 59-year-old-man. CGD diagnosis should be considered in adult patients with unexplained infectious diseases with tissue granuloma.
慢性肉芽肿病（CGD）是一种原发性免疫缺陷病，与多种危及生命的细菌和真菌感染相关，始于儿童期。成年期诊断出该病的情况较为罕见。我们在此描述两例成人晚期诊断病例：一名45岁女性和一名59岁男性。对于患有不明原因的伴有组织肉芽肿的感染性疾病的成年患者，应考虑CGD的诊断。
