Giardino Angela, Gupta Supriya, Olson Emmi, Sepulveda Karla, Lenchik Leon, Ivanidze Jana, Rakow-Penner Rebecca, Patel Midhir J, Subramaniam Rathan M, Ganeshan Dhakshinamoorthy
Department of Imaging, Dana-Farber Cancer Institute, Boston, Massachusetts; Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Department of Radiology and Imaging, Medical College of Georgia, 1120 15th St, Augusta, GA 30912.
Acad Radiol. 2017 May;24(5):639-649. doi: 10.1016/j.acra.2016.11.021. Epub 2017 Jan 25.
Precision medicine is an emerging approach for treating medical disorders, which takes into account individual variability in genetic and environmental factors. Preventive or therapeutic interventions can then be directed to those who will benefit most from targeted interventions, thereby maximizing benefits and minimizing costs and complications. Precision medicine is gaining increasing recognition by clinicians, healthcare systems, pharmaceutical companies, patients, and the government. Imaging plays a critical role in precision medicine including screening, early diagnosis, guiding treatment, evaluating response to therapy, and assessing likelihood of disease recurrence. The Association of University Radiologists Radiology Research Alliance Precision Imaging Task Force convened to explore the current and future role of imaging in the era of precision medicine and summarized its finding in this article. We review the increasingly important role of imaging in various oncological and non-oncological disorders. We also highlight the challenges for radiology in the era of precision medicine.
精准医学是一种新兴的治疗医学疾病的方法,它考虑到遗传和环境因素中的个体差异。然后,预防或治疗干预可以针对那些将从靶向干预中获益最大的人,从而使益处最大化,成本和并发症最小化。精准医学正越来越受到临床医生、医疗系统、制药公司、患者和政府的认可。影像学在精准医学中发挥着关键作用,包括筛查、早期诊断、指导治疗、评估治疗反应以及评估疾病复发的可能性。大学放射科医生协会放射学研究联盟精准成像特别工作组召开会议,探讨影像学在精准医学时代当前和未来的作用,并在本文中总结了其研究结果。我们回顾了影像学在各种肿瘤和非肿瘤疾病中日益重要的作用。我们还强调了精准医学时代放射学面临的挑战。