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[用于血液灌流的聚山梨酯。聚山梨酯表面改性对形态、凝血、纤维蛋白溶解和激肽释放酶形成的影响]

[Polysorbates for hemoperfusion. The effect of polysorbate surface modification on morphology, coagulation, fibrinolysis, and kallikrein formation].

作者信息

Kotschy M, Jurkowski P, Zekanowska E

机构信息

Katedra i Zakład Patofizjologii Akademii Medycznej w Bydgoszczy.

出版信息

Polim Med. 1989;19(1-2):37-47.

PMID:2813196
Abstract

In the work the influence of surface sulfonated polymer sorbents with styrene-divinylbenzene (Vinylsorb SS) modified by amino acids upon the morphological picture of blood and proteins of the coagulation system was tested. Those sorbents do not exert a remarkable influence upon erythrocytes and coagulation proteins but they adsorb blood platelets, leucocytes and they activate prekallikrein system. Vinylsorb SS has the best influence because it adsorbs few platelets and activates prekallikrein system to the least extent.

摘要

在这项工作中,测试了用氨基酸改性的苯乙烯 - 二乙烯基苯表面磺化聚合物吸附剂(Vinylsorb SS)对血液形态和凝血系统蛋白质的影响。这些吸附剂对红细胞和凝血蛋白没有显著影响,但它们能吸附血小板、白细胞并激活前激肽释放酶系统。Vinylsorb SS的影响最佳,因为它吸附的血小板最少,对前激肽释放酶系统的激活程度也最低。

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1
[Polysorbates for hemoperfusion. The effect of polysorbate surface modification on morphology, coagulation, fibrinolysis, and kallikrein formation].[用于血液灌流的聚山梨酯。聚山梨酯表面改性对形态、凝血、纤维蛋白溶解和激肽释放酶形成的影响]
Polim Med. 1989;19(1-2):37-47.
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