Kim M J, Berdanier C D
Department of Foods and Nutrition, University of Georgia, Athens 30602.
Proc Soc Exp Biol Med. 1989 Nov;192(2):172-6. doi: 10.3181/00379727-192-42974.
The effects of corn or menhaden oil and thyroxine treatment on hepatic mitochondrial respiration was studied. BHE rats were fed a 64% sucrose, 6% corn, or menhaden oil diet until they were 60-70 days of age. Succinate-supported mitochondrial respiration was studied at 3 degrees C intervals from 4 to 40 degrees C. Upper and lower activation energies and transition temperatures were determined through the calculation of Arrhenius plot. Menhaden oil plus daily thyroxine injection resulted in higher and lower activation energies than the other treatments. This combined treatment also resulted in lower state 3 and higher state 4 respiration rates and tighter coupling of respiration to ATP synthesis. These effects were thought to be due to the effect this treatment combination had on membrane fluidity.
研究了玉米油或鲱鱼油以及甲状腺素处理对肝脏线粒体呼吸的影响。将BHE大鼠喂以含64%蔗糖、6%玉米油或鲱鱼油的饲料，直至其60 - 70日龄。在4至40摄氏度范围内，每隔3摄氏度研究琥珀酸支持的线粒体呼吸。通过计算阿伦尼乌斯曲线确定上下活化能和转变温度。鲱鱼油加每日注射甲状腺素导致的活化能高于或低于其他处理。这种联合处理还导致较低的状态3和较高的状态4呼吸速率，以及呼吸与ATP合成的更紧密偶联。这些效应被认为是由于这种处理组合对膜流动性的影响。
