Van Hartesveldt C, Cottrell G A, Meyer M E
Psychology Department, University of Florida, Gainesville 32611.
Pharmacol Biochem Behav. 1989 Jun;33(2):321-4. doi: 10.1016/0091-3057(89)90507-8.
The effects of intracerebral implants of 17 beta estradiol and cholesterol in five brain regions were tested on the duration of the dorsal immobility response in ovariectomized female rats. The dorsal immobility response was significantly prolonged by 4-hr implants of 17 beta estradiol in the dorsal striatum and nucleus accumbens, but not in the cortex, the globus pallidus, or the substantia nigra pars compacta. These data further support previous evidence that estradiol acts directly on the striatum to affect behavior in the rat.
在去卵巢雌性大鼠中，测试了在五个脑区植入17β-雌二醇和胆固醇对背侧不动反应持续时间的影响。在背侧纹状体和伏隔核中植入4小时的17β-雌二醇可显著延长背侧不动反应，但在皮质、苍白球或黑质致密部则不然。这些数据进一步支持了先前的证据，即雌二醇直接作用于纹状体以影响大鼠的行为。
