使用荧光抗粘附抗体维多珠单抗对克罗恩病黏膜α4β7整合素表达进行分子成像。 - Suppr

Molecular imaging of mucosal α4β7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn's disease.

作者信息

Rath Timo, Bojarski Christian, Neurath Markus F, Atreya Raja

机构信息

Department of Medicine 1, Friedrich-Alexander University Erlangen-Nuernberg, Division of Gastroenterology, Endocrinology and Pneumology, Ludwig Demling Endoscopy Center of Excellence, Erlangen, Germany.

Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Department of Gastroenterology, Berlin, Germany.

出版信息

Gastrointest Endosc. 2017 Aug;86(2):406-408. doi: 10.1016/j.gie.2017.01.012. Epub 2017 Jan 27.

DOI:10.1016/j.gie.2017.01.012

PMID:28137597

Abstract

摘要

相似文献

Molecular imaging of mucosal α4β7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn's disease.使用荧光抗粘附抗体维多珠单抗对克罗恩病黏膜α4β7整合素表达进行分子成像。

Gastrointest Endosc. 2017 Aug;86(2):406-408. doi: 10.1016/j.gie.2017.01.012. Epub 2017 Jan 27.

[Vedolizumab in the treatment of Crohn's disease].[维多珠单抗治疗克罗恩病]

Gastroenterol Hepatol. 2015 May;38(5):338-48. doi: 10.1016/j.gastrohep.2014.12.003. Epub 2015 Jan 23.

Identification of Candidate Biomarkers Associated with Response to Vedolizumab in Inflammatory Bowel Disease.识别与 vedolizumab 在炎症性肠病中的应答相关的候选生物标志物。

Dig Dis Sci. 2018 Sep;63(9):2419-2429. doi: 10.1007/s10620-018-4924-8. Epub 2018 Jan 25.

Vedolizumab for ulcerative colitis and Crohn's disease: results and implications of GEMINI studies.维多珠单抗用于溃疡性结肠炎和克罗恩病：GEMINI研究的结果及意义

Immunotherapy. 2014;6(9):963-71. doi: 10.2217/imt.14.66.

The Anti-α4β7 Integrin Therapeutic Antibody for Inflammatory Bowel Disease, Vedolizumab, Ameliorates Eosinophilic Esophagitis: a Novel Clinical Observation.用于治疗炎症性肠病的抗α4β7整合素治疗性抗体维多珠单抗可改善嗜酸性食管炎：一项新的临床观察

Am J Gastroenterol. 2018 Aug;113(8):1261-1263. doi: 10.1038/s41395-018-0145-1. Epub 2018 Jun 12.

Vedolizumab Efficacy Is Associated With Decreased Intracolonic Dendritic Cells, Not Memory T Cells.维得利珠单抗的疗效与减少结内树突状细胞有关，而与记忆 T 细胞无关。

Inflamm Bowel Dis. 2024 May 2;30(5):704-717. doi: 10.1093/ibd/izad224.

Vedolizumab in the treatment of Crohn's disease.维多珠单抗治疗克罗恩病

Expert Rev Gastroenterol Hepatol. 2016;10(3):283-90. doi: 10.1586/17474124.2016.1135051. Epub 2016 Jan 25.

Efficacy and safety of vedolizumab in the treatment of ulcerative colitis.维多珠单抗治疗溃疡性结肠炎的疗效与安全性。

Gastroenterol Hepatol. 2016 Dec;39(10):677-686. doi: 10.1016/j.gastrohep.2015.11.010. Epub 2016 Mar 2.

Pharmacodynamic assessment of vedolizumab for the treatment of ulcerative colitis.维多珠单抗治疗溃疡性结肠炎的药效学评估。

Expert Opin Drug Metab Toxicol. 2016 Jul;12(7):833-42. doi: 10.1080/17425255.2016.1181171. Epub 2016 May 12.

Questions and answers about the management of Crohn's disease and ulcerative colitis with vedolizumab.关于维多珠单抗治疗克罗恩病和溃疡性结肠炎的问答

Gastroenterol Hepatol. 2019 Dec;42(10):650-656. doi: 10.1016/j.gastrohep.2019.08.007. Epub 2019 Oct 18.

引用本文的文献

Transforming Gastrointestinal Diagnosis with Molecular Endoscopy: Challenges and Opportunities.分子内镜技术在胃肠道诊断中的变革：挑战与机遇

Int J Mol Sci. 2025 May 18;26(10):4834. doi: 10.3390/ijms26104834.

Artificial Intelligence in Inflammatory Bowel Disease Endoscopy.炎症性肠病内镜检查中的人工智能

Diagnostics (Basel). 2025 Apr 1;15(7):905. doi: 10.3390/diagnostics15070905.

Artificial intelligence-enabled advanced endoscopic imaging to assess deep healing in inflammatory bowel disease.借助人工智能的先进内镜成像技术评估炎症性肠病的深部愈合情况。

eGastroenterology. 2024 Aug 1;2(3):e100090. doi: 10.1136/egastro-2024-100090. eCollection 2024 Sep.

Precision medicine in inflammatory bowel disease.炎症性肠病中的精准医学。

Precis Clin Med. 2023 Dec 18;6(4):pbad033. doi: 10.1093/pcmedi/pbad033. eCollection 2023 Dec.

Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease.荧光标记的维多珠单抗用于可视化炎症性肠病中的药物分布和黏膜靶细胞。

Gut. 2024 Aug 8;73(9):1454-1463. doi: 10.1136/gutjnl-2023-331696.

Confocal laser endomicroscopy as predictive biomarker of clinical and endoscopic efficacy of vedolizumab in ulcerative colitis: The DETECT study.共聚焦激光内镜检查作为维得利珠单抗治疗溃疡性结肠炎临床和内镜疗效的预测生物标志物：DETECT 研究。

PLoS One. 2024 Apr 2;19(4):e0298313. doi: 10.1371/journal.pone.0298313. eCollection 2024.

Biomarkers That Predict Crohn's Disease Outcomes.预测克罗恩病预后的生物标志物。

J Can Assoc Gastroenterol. 2023 Sep 2;7(1):59-67. doi: 10.1093/jcag/gwad024. eCollection 2024 Feb.

Precision Medicine in Inflammatory Bowel Disease.炎症性肠病中的精准医学

Diagnostics (Basel). 2023 Aug 29;13(17):2797. doi: 10.3390/diagnostics13172797.

Present and future of endoscopy precision for inflammatory bowel disease.炎症性肠病内镜精准化的现状与未来

Dig Endosc. 2024 Mar;36(3):292-304. doi: 10.1111/den.14672. Epub 2023 Sep 22.

Next-Generation Endoscopy in Inflammatory Bowel Disease.炎症性肠病的下一代内镜检查

Diagnostics (Basel). 2023 Jul 31;13(15):2547. doi: 10.3390/diagnostics13152547.

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Molecular imaging of mucosal α4β7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn's disease.

作者信息

Rath Timo, Bojarski Christian, Neurath Markus F, Atreya Raja

机构信息

Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Department of Gastroenterology, Berlin, Germany.

出版信息

Gastrointest Endosc. 2017 Aug;86(2):406-408. doi: 10.1016/j.gie.2017.01.012. Epub 2017 Jan 27.

DOI:10.1016/j.gie.2017.01.012

PMID:28137597

Abstract

摘要

Molecular imaging of mucosal α4β7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn's disease.

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Molecular imaging of mucosal α4β7 integrin expression with the fluorescent anti-adhesion antibody vedolizumab in Crohn's disease.

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