Pfeffer F, Avilas Rosas H, Vargas F, Villalobos J J
Rev Invest Clin. 1989 Jul-Sep;41(3):205-8.
The purpose of this study was to evaluate retrospectively the role of alcohol intake, smoking and coffee consumption as risk factors in the development of cancer of the pancreas. Twenty nine cases with pancreatic cancer and 29 controls matched by sex, socioeconomic status and age were evaluated. Information on alcohol, tobacco and coffee consumption was obtained by specially designed questionnaires. Odds ratios were calculated and analyzed by chi square testing. The combination of the 3 factors gave an odds ratio of 26.3, whereas alcohol and coffee consumption gave an odds ratio of 13.9. Considered independently, only alcohol and coffee consumption were found to be significantly associated with cancer of the pancreas.
本研究的目的是回顾性评估饮酒、吸烟和咖啡饮用作为胰腺癌发生风险因素的作用。对29例胰腺癌患者和29例按性别、社会经济地位和年龄匹配的对照者进行了评估。通过专门设计的问卷获取有关饮酒、吸烟和咖啡饮用的信息。计算比值比并通过卡方检验进行分析。这3个因素共同作用时的比值比为26.3,而饮酒和咖啡饮用的比值比为13.9。单独考虑时,仅发现饮酒和咖啡饮用与胰腺癌显著相关。