Li Na, Wang Yumei, Yu Lulu, Song Mei, Wang Lan, Ji Chunpeng, Wang Xueyi, Wu Shouling
Department of Mental Health, the First Hospital of Hebei Medical University, Hebei Medical University Institute of Mental Health, Shijiazhuang, China.
Department of Cardiology, Kailuan General Hospital, Tangshan, China.
Arch Med Sci. 2017 Feb 1;13(1):75-81. doi: 10.5114/aoms.2017.64716. Epub 2016 Dec 19.
The aim of the study was to study the long-term effect on cardiovascular disease risk factors of stress from direct experience of an earthquake as a young person.
We selected workers born between July 1, 1958 and July 1, 1976 who were examined at Kailuan General Hospital between May and October of 2013. Data on cardiovascular events were taken during the workers' annual health examination conducted between 2006 and 2007. All subjects were divided into three groups according to their experience of the Tangshan earthquake of July 28, 1976, as follows: control group; exposed group 1 and exposed group 2. We compared cardiovascular disease risk factors between the three groups as well as by gender and age.
One thousand one hundred and ninety-six workers were included in the final statistical analysis. Among all subjects, resting heart rate ( = 0.003), total cholesterol ( < 0.001), and fasting blood glucose ( < 0.001) were significantly higher among those who experienced the earthquake compared with unexposed controls, but were unrelated to loss of relatives. No significant difference in triglyceride levels was observed between the three groups ( = 0.900). Further refinement showed that the effects were restricted to males 40 years of age or older at the time of analysis, but were due primarily to age at the time of earthquake exposure ( = 0.002, < 0.001 and = 0.002).
Earthquake experience in the early years of life has long-term effects on adult resting heart rate, total cholesterol, and fasting plasma glucose, especially among men.
本研究的目的是探讨年轻时直接经历地震所产生的压力对心血管疾病风险因素的长期影响。
我们选取了1958年7月1日至1976年7月1日出生、于2013年5月至10月期间在开滦总医院接受检查的工人。心血管事件数据取自2006年至2007年期间对这些工人进行的年度健康检查。所有受试者根据其1976年7月28日唐山地震的经历分为三组，如下：对照组；暴露组1和暴露组2。我们比较了三组之间以及按性别和年龄划分的心血管疾病风险因素。
1196名工人纳入最终统计分析。在所有受试者中，与未暴露的对照组相比，经历过地震的人静息心率（P = 0.003）、总胆固醇（P < 0.001）和空腹血糖（P < 0.001）显著更高，但与亲属丧失无关。三组之间甘油三酯水平未观察到显著差异（P = 0.900）。进一步细化显示，这些影响仅限于分析时年龄在40岁及以上的男性，但主要归因于地震暴露时的年龄（P = 0.002，P < 0.001和P = 0.002）。
早年经历地震对成年人静息心率、总胆固醇和空腹血糖有长期影响，尤其是在男性中。
