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人工关节周围髋膝关节感染的一期翻修置换术

One-stage Exchange Arthroplasty for Periprosthetic Hip and Knee Joint Infections.

作者信息

Nguyen Manny, Sukeik Mohamed, Zahar Akos, Nizam Ikram, Haddad Fares Sami

机构信息

Ozorthopaedics, Hospital in Malvern, 1356 High Street Malvern, VIC 3144, Australia.

Department of Trauma and Orthopaedics, The Royal London Hospital, Whitechapel, London, E1 1BB, United Kingdom.

出版信息

Open Orthop J. 2016 Nov 30;10:646-653. doi: 10.2174/1874325001610010646. eCollection 2016.

Abstract

BACKGROUND

Periprosthetic joint infection (PJI) is a devastating complication of joint replacement surgery. In an aging population of the developed world, the increasing numbers of hip and knee replacements will inevitably lead to increasing incidence of PJI, carrying with (it) significant patient morbidity and cost to the health care system. Two-stage exchange arthroplasty is currently the gold standard but it is associated with multiple operations, prolonged hospitalization and impaired functionality. One-stage exchange arthroplasty is similar to the two-stage procedure but the interval between removal of the prosthesis and reimplantation of a new one is only a few minutes. It has the theoretical benefits of a single anesthetic, shorter hospitalization, less cost and improved function.

METHODS

We reviewed the current literature regarding the outcomes of one-stage exchange arthroplasties focusing on re-infection rates and functional outcomes.

RESULTS

Current themes around the one-stage exchange procedure include the indications for the procedure, definition of re-infection, surgical techniques used to provide fixation and differences in approach for hip and knee replacements.

CONCLUSION

The current literature on one-stage exchange procedure is promising, with comparable results to two-stage revisions for hips and knees in selected patients. However, there is a great need for a large multi-centred randomized control trial, focusing on re-infection rates and functional scores postoperatively, to provide concrete guidelines in managing this complex condition.

摘要

背景

人工关节周围感染(PJI)是关节置换手术的一种严重并发症。在发达国家老龄化人口中,髋膝关节置换数量的增加将不可避免地导致PJI发病率上升,给患者带来严重的发病风险,并给医疗保健系统带来成本负担。两阶段翻修关节成形术目前是金标准,但它与多次手术、住院时间延长和功能受损有关。一阶段翻修关节成形术与两阶段手术类似,但假体取出与新假体重新植入之间的间隔仅几分钟。它具有单次麻醉、住院时间短、成本低和功能改善等理论优势。

方法

我们回顾了当前关于一阶段翻修关节成形术结果的文献,重点关注再感染率和功能结果。

结果

围绕一阶段翻修手术的当前主题包括该手术的适应症、再感染的定义、用于提供固定的手术技术以及髋膝关节置换手术方法的差异。

结论

目前关于一阶段翻修手术的文献很有前景,在选定患者中,髋膝关节的结果与两阶段翻修相当。然而,迫切需要进行一项大型多中心随机对照试验,重点关注术后再感染率和功能评分,以提供管理这种复杂病症的具体指南。

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