Department of Pharmacy, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
School of Chemical Engineering, University of Birmingham, Edgbaston, B15 2TT, UK.
Adv Mater. 2017 Apr;29(13). doi: 10.1002/adma.201605594. Epub 2017 Feb 1.
A method for the production of complex cell-laden structures is reported, which allows high-levels of spatial control over mechanical and chemical properties. The potential of this method for producing complicated tissues is demonstrated by manufacturing a complex hard/soft tissue interface and demonstrating that cell phenotype can be maintained over four weeks of culture.
现报道一种制造复杂细胞载体结构的方法,该方法可实现对力学和化学性能的高度空间控制。通过制造复杂的硬/软组织界面并证明细胞表型在 4 周的培养过程中得以维持,证明了该方法在制造复杂组织方面的潜力。