Vance Vivienne, Campbell Sharon, Mccargar Linda, Mourtzakis Marina, Hanning Rhona
a Department of Health Sciences, Wilfrid Laurier University, Waterloo, ON.
b School of Public Health and Health Systems, University of Waterloo, Waterloo, ON.
Can J Diet Pract Res. 2017 Jun 1;78(2):74-80. doi: 10.3148/cjdpr-2016-034. Epub 2017 Feb 1.
This study investigated relationships between psychosocial and treatment-related factors, diet, and weight change in women treated with chemotherapy for early-stage breast cancer.
Comprehensive qualitative interviews were conducted with 28 women who were within 12 months of completing chemotherapy treatment.
Changes in food intake and eating patterns were universal over the course of chemotherapy, with broad variability in treatment effects and associated dietary responses linked to weight change. Increased appetite, food cravings, and intake of energy-dense comfort foods were more common among women who gained weight during treatment (n = 11). Changes in taste, nausea, and emotional distress were central in promoting these dietary responses. Women who lost weight during treatment (n = 6) tended to report more severe and persistent side effects of treatment leading to poor appetite and lower food intake, and they were more likely to live alone.
While the etiology of weight change in this population is complex, this study suggests that changes in food intake related to treatment and psychosocial challenges may play an important role for some women. These findings may help to identify women who are most at risk of weight change during treatment and may inform the development of tailored dietary interventions.
本研究调查了早期乳腺癌化疗女性患者心理社会因素、治疗相关因素、饮食与体重变化之间的关系。
对28名在完成化疗治疗后12个月内的女性进行了全面的定性访谈。
在化疗过程中,食物摄入量和饮食模式的变化普遍存在,治疗效果和与体重变化相关的饮食反应存在广泛差异。食欲增加、食物渴望以及摄入能量密集型安慰食品在治疗期间体重增加的女性中更为常见(n = 11)。味觉变化、恶心和情绪困扰是促使这些饮食反应的核心因素。治疗期间体重减轻的女性(n = 6)往往报告治疗的副作用更严重且持续时间更长,导致食欲不佳和食物摄入量减少,并且她们更有可能独居。
虽然该人群体重变化的病因复杂,但本研究表明,与治疗和心理社会挑战相关的食物摄入量变化可能对一些女性起着重要作用。这些发现可能有助于识别治疗期间体重变化风险最高的女性,并为制定个性化饮食干预措施提供参考。