英国学校流感爆发的社会和经济影响：照顾者调查

Social and Economic Impacts of School Influenza Outbreaks in England: Survey of Caregivers.

作者信息

Thorrington Dominic, Balasegaram Sooria, Cleary Paul, Hay Catherine, Eames Ken

机构信息

London School of Hygiene and Tropical Medicine, Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

Public Health England, Field Epidemiology Services London, 151 Buckingham Palace Road, London SW1W 9SZ, UK.

出版信息

J Sch Health. 2017 Mar;87(3):209-216. doi: 10.1111/josh.12484.

DOI:10.1111/josh.12484

PMID:28147460

Abstract

BACKGROUND

Influenza is a cause of considerable morbidity in England, particularly among children. A total of 39% of all influenza-attributable general practitioner consultations and 37% of all influenza-attributable hospital admissions occur in those aged under 15 years. Few studies have quantified the impact of influenza outbreaks on families. We assessed this impact during 2 influenza seasons.

METHODS

We used questionnaires to obtain data in primary schools that reported an outbreak of an influenza-like-illness (ILI). We sought data on the loss of productivity, costs borne by families and loss in health-related quality of life (HRQoL). ILIs were identified using the symptoms criteria from the European Centre for Disease Prevention and Control and the UK Flusurvey.

RESULTS

For each child reporting ILI, mean school absence was 3.8 days (95% confidence interval [CI]): 3.0-4.8) with mean work absence for caregivers reported as 3.7 days (95% CI: 2.7-4.8). The mean loss in HRQoL was 2.1 quality-adjusted life days (95% CI: 1.5-2.7). The estimated total pediatric burden of disease for reported school-based outbreaks during the 2 influenza seasons was 105.3 QALYs (95% CI: 77.7-139.0).

CONCLUSIONS

This study shows the potential social and economic benefit of vaccination of children during mild influenza seasons.

摘要

背景

在英国，流感是导致大量发病的原因，尤其是在儿童中。所有因流感导致的全科医生诊疗中，39%发生在15岁以下人群，所有因流感导致的住院病例中，37%发生在15岁以下人群。很少有研究对流感暴发对家庭的影响进行量化。我们评估了两个流感季节期间的这种影响。

方法

我们通过问卷调查在报告了流感样疾病（ILI）暴发的小学中获取数据。我们收集了关于生产力损失、家庭承担的费用以及健康相关生活质量（HRQoL）损失的数据。使用欧洲疾病预防控制中心和英国流感调查的症状标准来确定ILI。

结果

对于每例报告患ILI的儿童，平均缺课天数为3.8天（95%置信区间[CI]：3.0 - 4.8），照顾者的平均误工天数报告为3.7天（95%CI：2.7 - 4.8）。HRQoL的平均损失为2.1个质量调整生命天数（95%CI：1.5 - 2.7）。在两个流感季节期间，报告的学校暴发中估计的儿童疾病总负担为105.3个质量调整生命年（95%CI：77.7 - 139.0）。