Colombo Marco, Beltrami Riccardo, Rattalino Davide, Mirando Maria, Chiesa Marco, Poggio Claudio
Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, Section of Dentistry, University of Pavia, Italy.
Ann Stomatol (Roma). 2017 Jan 10;7(3):38-45. doi: 10.11138/ads/2016.7.3.038. eCollection 2016 Jul-Sep.
The aim of the present study was to evaluate the protective effects of a zinc-hydroxyapatite toothpaste against an erosive challenge produced by a soft drink (Coca-Cola) using Scanning Electron Microscopy (SEM).
Forty specimens were assigned to 4 groups of 10 specimens each (group 1: no erosive challenge, no toothpaste treatment, group 2: erosive challenge, no toothpaste treatment, group 3: erosive challenge, fluoride toothpaste treatment, group 4: erosive challenge, zinc-hydroxyapatite toothpaste treatment). The surface of each specimen was imaged by SEM. A visual rating system was used to evaluate the condition of the enamel surface; results were analyzed by nonparametric statistical methods.
Statistically significant differences were found between the samples untreated and those immersed in Coca-Cola (group 1, 2); the highest grade of damage was found in group 2, while the lowest grade was recorded in the samples of group 4. Comparing the groups, the two analyzed toothpaste tended to protect in different extend.
In this study treatment of erosively challenged enamel with Zn-Hap toothpaste showed a clear protective effect. This was greater than the effect observed for a normal fluoride toothpaste and confirmed the potential benefit the Zn-HAP technology can provide in protecting enamel from erosive acid challenges.
本研究旨在使用扫描电子显微镜（SEM）评估含锌羟基磷灰石牙膏对软饮料（可口可乐）造成的侵蚀性挑战的保护作用。
40个样本被分为4组，每组10个样本（第1组：无侵蚀性挑战，未用牙膏处理；第2组：有侵蚀性挑战，未用牙膏处理；第3组：有侵蚀性挑战，用含氟牙膏处理；第4组：有侵蚀性挑战，用含锌羟基磷灰石牙膏处理）。通过扫描电子显微镜对每个样本的表面进行成像。使用视觉评级系统评估牙釉质表面状况；结果采用非参数统计方法进行分析。
未处理样本与浸泡在可口可乐中的样本（第1组、第2组）之间存在统计学上的显著差异；第2组损伤程度最高，而第4组样本损伤程度最低。比较各实验组，两种牙膏的保护程度不同。
在本研究中，用含锌羟基磷灰石牙膏处理受侵蚀的牙釉质显示出明显的保护作用。这种保护作用大于普通含氟牙膏的效果，并证实了含锌羟基磷灰石技术在保护牙釉质免受侵蚀性酸侵蚀方面的潜在益处。
