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一例使用贝利尤单抗治疗的狼疮患者发生中枢神经系统诺卡菌病的病例。

A case of central nervous system nocardiosis in a patient with lupus treated with belimumab.

作者信息

Lai Richard Hc, Kim Deborah, Constantinescu Florina

机构信息

Department of Rheumatology, Medstar Washington Hospital Center, Washington, USA.

Department of Rheumatology, Medstar Washington Hospital Center, Washington, USA; Department of Clinical Medicine, Georgetown University Medical, Center, Washington, USA.

出版信息

Eur J Rheumatol. 2016 Dec;3(4):188-190. doi: 10.5152/eurjrheum.2016.15083. Epub 2016 Dec 1.

Abstract

Belimumab was approved by the United States Food and Drug Administration in March 2011 as the first biological agent for treating active systemic lupus erythematosus (SLE). To the best of our knowledge, this is the first case report regarding a patient with SLE treated with belimumab who was diagnosed with central nervous system nocardiosis.

摘要

贝利尤单抗于2011年3月获美国食品药品监督管理局批准,成为首个用于治疗活动性系统性红斑狼疮(SLE)的生物制剂。据我们所知,这是首例关于使用贝利尤单抗治疗的SLE患者被诊断为中枢神经系统诺卡菌病的病例报告。

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本文引用的文献

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Belimumab for systemic lupus erythematosus.贝利尤单抗治疗系统性红斑狼疮。
N Engl J Med. 2013 Apr 18;368(16):1528-35. doi: 10.1056/NEJMct1207259.
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Changing trends in infectious disease in heart transplantation.心脏移植中感染性疾病的变化趋势。
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Nocardiosis in systemic lupus erythematosus.系统性红斑狼疮中的诺卡菌病
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Nocardiosis.诺卡菌病
Clin Infect Dis. 1996 Jun;22(6):891-903; quiz 904-5. doi: 10.1093/clinids/22.6.891.
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Nocardial meningitis: case reports and review.
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