Faraji Reza, Behjati-Ardakani Mostafa, Moshtaghioun Seyed Mohammad, Kalantar Seyed Mehdi, Namayandeh Seyedeh Mahdieh, Soltani Mohammadhossien, Zandi Hengameh, Firoozabadi Ali Dehghani, Tavakkoli Banizi Neda, Kahtooie Foroozandeh Qasemi, Banaei Mehdi, Sarebanhassanabadi Mohammadtaghi
Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Department of Biology, Faculty of Science, Yazd University, Yazd, Iran.
GMS Hyg Infect Control. 2017 Jan 16;12:Doc01. doi: 10.3205/dgkh000286. eCollection 2017.
Infective endocarditis (IE) is a microbial infection of heart valves and its endothelial lining which is considered as a life-threatening disorder. This study evaluated the epidemiological, clinical, and microbiological features of IE at the Cardiovascular Research Center in Yazd, Iran. The cross-sectional study was conducted on 20 patients diagnosed with definite IE on the basis of Duke's criteria hospitalized for one year in the Cardiovascular Research Center in Yazd, Iran, from January 2015 to December 2015. Demographic information, clinical, laboratory, and microbiological findings, and also trans-esophageal echocardiography (TEE) of each patient were recorded and assessed. The collected data were analyzed using SPSS 16. The mean age of the patients under study was 45±16 years with most of the afflicted patients (60%) being male. Most cases (70%) of IE were observed in the warm seasons (spring and summer). The most common clinical sign (80%) was fever. TEE was positive for all (100%) patients, and vegetation was seen in all patients. The nosocomial mortality rate was zero. However, 14 (70%) patients underwent surgical treatment. The valves afflicted with IE were: the mitral valve (40%), the aortic valve (35%), and the tricuspid valve (25%), respectively. 4 patients (20%) had a positive history of IE. Blood culture test was positive only in 1 case and the isolated microorganism belonged to the viridans group streptococci. Despite the one-year high prevalence of IE in this study, the nosocomial mortality rate was not high and was reported to be nil under surgical and antimicrobial therapy.
感染性心内膜炎（IE）是心脏瓣膜及其内皮衬里的微生物感染，被认为是一种危及生命的疾病。本研究评估了伊朗亚兹德心血管研究中心IE的流行病学、临床和微生物学特征。该横断面研究对2015年1月至2015年12月期间在伊朗亚兹德心血管研究中心住院一年、根据杜克标准被诊断为确诊IE的20例患者进行。记录并评估了每位患者的人口统计学信息、临床、实验室和微生物学检查结果，以及经食管超声心动图（TEE）检查结果。使用SPSS 16对收集的数据进行分析。研究对象的平均年龄为45±16岁，大多数患病患者（60%）为男性。IE的大多数病例（70%）在温暖季节（春季和夏季）被观察到。最常见的临床症状（80%）是发热。所有患者（100%）的TEE检查均为阳性，且所有患者均可见赘生物。医院死亡率为零。然而，14例（70%）患者接受了手术治疗。受IE影响的瓣膜分别为：二尖瓣（40%）、主动脉瓣（35%）和三尖瓣（25%）。4例患者（20%）有IE病史阳性。血培养检查仅1例呈阳性，分离出的微生物属于草绿色链球菌。尽管本研究中IE的患病率在一年内较高，但医院死亡率并不高，据报道在手术和抗菌治疗下为零。
