Pillich Rudolf T, Chen Jing, Rynkov Vladimir, Welker David, Pratt Dexter
UC San Diego Center for Computational Biology and Bioinformatics (MC 0681), University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Methods Mol Biol. 2017;1558:271-301. doi: 10.1007/978-1-4939-6783-4_13.
Networks are a powerful and flexible paradigm that facilitate communication and computation about interactions of any type, whether social, economic, or biological. NDEx, the Network Data Exchange, is an online commons to enable new modes of collaboration and publication using biological networks. NDEx creates an access point and interface to a broad range of networks, whether they express molecular interactions, curated relationships from literature, or the outputs of systematic analysis of big data. Research organizations can use NDEx as a distribution channel for networks they generate or curate. Developers of bioinformatic applications can store and query NDEx networks via a common programmatic interface. NDEx can also facilitate the integration of networks as data in electronic publications, thus making a step toward an ecosystem in which networks bearing data, hypotheses, and findings flow seamlessly between scientists.
网络是一种强大且灵活的范式，它有助于就任何类型的相互作用进行通信和计算，无论是社会、经济还是生物方面的相互作用。网络数据交换平台（NDEx）是一个在线共享平台，旨在利用生物网络实现新的协作和发布模式。NDEx创建了一个接入点和接口，可连接到广泛的网络，无论这些网络表达的是分子相互作用、从文献中整理的关系，还是大数据系统分析的输出结果。研究机构可以将NDEx用作其生成或整理的网络的分发渠道。生物信息学应用程序的开发者可以通过通用的编程接口存储和查询NDEx网络。NDEx还可以促进网络作为电子出版物中的数据进行整合，从而朝着一个生态系统迈进，在这个生态系统中，承载数据、假设和发现的网络在科学家之间无缝流动。
