NDEx 2.0：癌症通路研究信息交换中心。
NDEx 2.0: A Clearinghouse for Research on Cancer Pathways.
作者信息
Pratt Dexter, Chen Jing, Pillich Rudolf, Rynkov Vladimir, Gary Aaron, Demchak Barry, Ideker Trey
机构信息
Department of Medicine, University of California San Diego, La Jolla, California.
Department of Computer Science and Engineering, University of California San Diego, La Jolla, California.
出版信息
Cancer Res. 2017 Nov 1;77(21):e58-e61. doi: 10.1158/0008-5472.CAN-17-0606.
We present NDEx 2.0, the latest release of the Network Data Exchange (NDEx) online data commons (www.ndexbio.org) and the ways in which it can be used to (i) improve the quality and abundance of biological networks relevant to the cancer research community; (ii) provide a medium for collaboration involving networks; and (iii) facilitate the review and dissemination of networks. We describe innovations addressing the challenges of an online data commons: scalability, data integration, data standardization, control of content and format by authors, and decentralized mechanisms for review. The practical use of NDEx is presented in the context of a novel strategy to foster network-oriented communities of interest in cancer research by adapting methods from academic publishing and social media. .
我们展示了网络数据交换（NDEx）在线数据共享平台（www.ndexbio.org）的最新版本NDEx 2.0，以及它可用于以下方面的方式：（i）提高与癌症研究社区相关的生物网络的质量和数量；（ii）提供一个涉及网络的协作媒介；（iii）促进网络的审查和传播。我们描述了应对在线数据共享平台挑战的创新举措：可扩展性、数据集成、数据标准化、作者对内容和格式的控制以及分散的审查机制。通过采用学术出版和社交媒体的方法，在一种促进癌症研究中以网络为导向的兴趣社区的新策略背景下展示了NDEx的实际应用。
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