Saito Ako, Hirata Tetsuya, Koga Kaori, Takamura Masashi, Fukuda Shinya, Neriishi Kazuaki, Pastorfide Gia, Harada Miyuki, Hirota Yasushi, Wada-Hiraike Osamu, Fujii Tomoyuki, Osuga Yutaka
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
J Obstet Gynaecol Res. 2017 Feb;43(2):320-329. doi: 10.1111/jog.13198.
Our objective was to determine the preoperative factors associated with difficulty in total laparoscopic hysterectomy (TLH).
This retrospective clinical study included 157 patients who underwent TLH for leiomyoma or adenomyosis between 2009 and 2013. All patients underwent magnetic resonance imaging (MRI) before surgery. We categorized patients as 'difficult' if the operation time was > 243 min, if total blood loss was > 500 mL, or if conversion to laparotomy was necessary. Preoperative information, including MRI findings, was compared between the difficult and 'other' patients. Stepwise logistic regression analysis was used to control for covariates that were significant on univariate analysis (P < 0.05).
The presence of an endometrioma, a previous cesarean section (CS), a wide uterus, and a high body mass index were independent risk factors for being a difficult patient. For adenomyosis patients, the presence of an endometrioma, a prior CS, subtype II adenomyosis, and high body mass index were independent risk factors for being a difficult patient. For leiomyoma patients, the presence of an endometrioma, a prior CS, and having at least seven leiomyomas were independent risk factors for being a difficult patient. All laparotomy conversion patients had multiple risk factors.
We have elucidated the factors associated with difficult TLH patients using patients' background and preoperative MRI findings. Awareness of these predictive factors may enable surgeons to prepare for the operation, minimize complications, or choose another more appropriate route of hysterectomy than TLH.
我们的目标是确定与全腹腔镜子宫切除术(TLH)困难相关的术前因素。
这项回顾性临床研究纳入了2009年至2013年间因子宫肌瘤或子宫腺肌病接受TLH的157例患者。所有患者术前均接受了磁共振成像(MRI)检查。如果手术时间>243分钟、总失血量>500毫升或需要转为开腹手术,我们将患者分类为“困难”组。比较“困难”组和“其他”组患者的术前信息,包括MRI检查结果。采用逐步逻辑回归分析来控制单因素分析中有显著意义的协变量(P<0.05)。
存在子宫内膜异位症、既往剖宫产史、子宫宽大和高体重指数是成为困难患者的独立危险因素。对于子宫腺肌病患者,存在子宫内膜异位症、既往剖宫产史、II型子宫腺肌病亚型和高体重指数是成为困难患者的独立危险因素。对于子宫肌瘤患者,存在子宫内膜异位症、既往剖宫产史和至少有七个子宫肌瘤是成为困难患者的独立危险因素。所有转为开腹手术的患者都有多个危险因素。
我们利用患者背景和术前MRI检查结果阐明了与困难TLH患者相关的因素。了解这些预测因素可能使外科医生为手术做好准备,将并发症降至最低,或选择比TLH更合适的子宫切除途径。