Barth P G
Afd. Kinderneurologie, EKZ, het Kinder AMC, Amsterdam.
Tijdschr Kindergeneeskd. 1989 Oct;57(5):197-202.
Neocortical dysplasia is the morphological expression of neocortical malformation. Its expression prevails in the areas surrounding the Sylvian fossa (opercula). Delayed opercularization, abnormal inclination angle of the Sylvian fissure and abnormal gyral patterns surrounding the fossa are the main abnormalities, made visible by MRI-sections, especially the lateral projections. The present study, which is part of a broader study on neocortical maldevelopment, involves the search for correlations between macroscopic and microscopic neocortical dysplasia, with the object of improving MRI diagnosis of neocortical dysplasia.
新皮质发育异常是新皮质畸形的形态学表现。其表现主要出现在外侧裂窝(岛盖)周围区域。岛盖发育延迟、外侧裂倾斜角度异常以及裂窝周围脑回模式异常是主要异常表现,通过MRI切片尤其是矢状面投影可清晰显示。本研究作为关于新皮质发育异常的一项更广泛研究的一部分,旨在探寻新皮质发育异常的宏观与微观表现之间的相关性,目的是改进新皮质发育异常的MRI诊断。