Nagata Kohei, Tajiri Kazuto, Shimada Seitarou, Ando Takayuki, Hosokawa Ayumu, Matsui Koshi, Imura Joji, Sugiyama Toshiro
The Third Department of Internal Medicine, Toyama University Hospital, Japan.
Intern Med. 2017;56(3):289-293. doi: 10.2169/internalmedicine.56.7523. Epub 2017 Feb 1.
Rectal neuroendocrine tumor (NET) is a relatively rare tumor. NET is classified as G1, G2, or G3 according to the degree of mitosis or Ki-67 proliferation index, which reflect the malignant potential of the tumor, such as metastasis. Advanced cases with metastasis are indicated for chemotherapy treatment. However, the efficacy of chemotherapy is limited. Therefore, resection is considered, even in metastatic cases, if complete resection is possible. We herein report a case of small rectal NET discovered with hepatic metastasis classified as G1. The patient showed good progress with no recurrence after undergoing hepatectomy and endoscopic resection of rectal NET.
直肠神经内分泌肿瘤(NET)是一种相对罕见的肿瘤。根据有丝分裂程度或Ki-67增殖指数,NET被分为G1、G2或G3级,这些指标反映了肿瘤的恶性潜能,如转移情况。有转移的晚期病例需进行化疗。然而,化疗的疗效有限。因此,即使是转移性病例,如果有可能完全切除,也会考虑进行手术切除。我们在此报告一例发现有肝转移的直肠小NET,分级为G1。该患者在接受肝切除和直肠NET内镜切除术后进展良好,无复发。