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摩根氏摩根菌致多发性骨髓瘤患者发生致命性横纹肌溶解症

Fatal Rhabdomyolysis Caused by Morganella morganii in a Patient with Multiple Myeloma.

作者信息

Imataki Osamu, Uemura Makiko

机构信息

Division of Hematology and Stem Cell Transplantation, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Japan.

出版信息

Intern Med. 2017;56(3):369-371. doi: 10.2169/internalmedicine.56.7252. Epub 2017 Feb 1.

Abstract

A 64-year-old Japanese man with multiple myeloma was admitted to our institute due to fever and hypotension. He had received multiple courses of chemotherapy just before his febrile episode. Blood culturing detected Morganella morganii. At the time of the diagnosis, his laboratory findings revealed massive rhabdomyolysis with a significantly increased creatinine kinase level (CK; 3,582 U/L); 98.8% of which corresponded to the CK-MB isotype. We diagnosed the patient with sepsis caused by M. morganii, complicated with severe rhabdomyolysis. He died of multi-organ failure 2 days later. Clinicians should closely observe patients with possible systemic infection-associated rhabdomyolysis.

摘要

一名64岁的日本男性多发性骨髓瘤患者因发热和低血压入住我院。他在发热发作前刚刚接受了多疗程化疗。血培养检测到摩根摩根菌。诊断时,他的实验室检查结果显示大量横纹肌溶解,肌酸激酶水平显著升高(CK;3582 U/L);其中98.8%对应CK-MB同型。我们诊断该患者为摩根摩根菌引起的败血症,并发严重横纹肌溶解。两天后,他死于多器官衰竭。临床医生应密切观察可能与全身感染相关的横纹肌溶解患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efa1/5348465/48ae1b5d4e7e/1349-7235-56-0369-g001.jpg

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