Singh U, Scheld W M
Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
Clin Infect Dis. 1996 Apr;22(4):642-9. doi: 10.1093/clinids/22.4.642.
Rhabdomyolysis can be precipitated by trauma, ischemia, metabolic defects, electrolyte abnormalities, drugs, and a wide variety of infectious diseases. At our institution, recent cases of rhabdomyolysis induced by influenza prompted us to review the infectious etiologies of this entity. In addition, a thorough literature search revealed numerous case reports but no general review on this subject. This study describes representative recent cases from our institution and details the wide variety of infections that can cause muscle damage. The pathophysiological mechanisms, muscle histology, and correlation with renal dysfunction are also discussed.
横纹肌溶解症可由创伤、缺血、代谢缺陷、电解质异常、药物以及多种传染病引发。在我们机构,近期流感诱发横纹肌溶解症的病例促使我们回顾该病症的感染性病因。此外,全面的文献检索发现了众多病例报告,但尚无关于此主题的综述。本研究描述了我们机构近期的典型病例,并详述了可导致肌肉损伤的多种感染。还讨论了其病理生理机制、肌肉组织学以及与肾功能不全的相关性。