Nakamura Yuka, Kanemoto Erika, Kajizono Makoto, Kitamura Yoshihisa, Sendo Toshiaki
Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Okayama University.
Yakugaku Zasshi. 2017;137(2):241-246. doi: 10.1248/yakushi.16-00226.
Cancer patients often develop mental conditions, including anxiety and depressive disorder. And, patients with chemotherapy often exhibit mental changes including anxiety and depressive disorder. Furthermore, it is well known that the frequency of delirium is increased in cancer patients receiving terminal care. Thus, the psychiatric and cognitive functions of cancer survivors are significantly influenced by their quality of life. In this study, we performed a retrospective analysis to identify the risk factors for psychiatric disorders in lung cancer survivors. Most lung cancer survivors that were diagnosed with psychiatric disorders had stage 4 disease. In addition, it was found that an increase in disease stage and high doses of opioids are associated with an increased risk of psychiatric disorders in lung cancer survivors. These findings suggest that it is necessary to consider the mental changes experienced by lung cancer patients during disease progression.
癌症患者常出现精神状况,包括焦虑和抑郁障碍。而且,接受化疗的患者常表现出包括焦虑和抑郁障碍在内的精神变化。此外,众所周知,接受临终关怀的癌症患者谵妄的发生率会增加。因此,癌症幸存者的精神和认知功能受到其生活质量的显著影响。在本研究中,我们进行了一项回顾性分析,以确定肺癌幸存者精神障碍的危险因素。大多数被诊断患有精神障碍的肺癌幸存者处于4期疾病。此外,还发现疾病分期增加和高剂量阿片类药物与肺癌幸存者精神障碍风险增加有关。这些发现表明,有必要考虑肺癌患者在疾病进展过程中经历的精神变化。