Department of Psychiatry, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Asian J Psychiatr. 2021 Mar;57:102563. doi: 10.1016/j.ajp.2021.102563. Epub 2021 Jan 28.
Patients hospitalized with COVID-19 are at risk of developing many neuropsychiatric disorders, due to the effects of the disease on the brain and the psychosocial pressures of having the disease. The aim of the present study was to evaluate the characteristics and outcomes of patients who were hospitalized with a diagnosis of COVID-19, who underwent psychiatric consultations. The medical records of 892 patients hospitalized due to COVID-19 and the 89 among them who requested psychiatric consultations were analyzed retrospectively. After the psychiatric consultations, patients were most frequently diagnosed with delirium (38.2 %), adjustment disorder (27.0 %), depressive disorder (19.1 %) and anxiety disorder (11.2 %). Patients with delirium had longer hospital stays (p < 0.001), were transferred more frequently to intensive care units (p < 0.001), and had higher mortality rates during their hospital stays (p < 0.001), than all other patients. The need for oxygen (p < 0.001) and mechanical ventilation (p < 0.001) was also significantly higher in delirium patients, as well as in patients who received other psychiatric diagnoses. Neuropsychiatric disorders develop in patients receiving inpatient treatments in COVID-19 wards, and these disorders negatively affect the prognosis of COVID-19. Our findings suggest that the presence of neuropsychiatric disorders in in-patients with COVID-19 might be associated with the negative outcomes of the disease.
因 COVID-19 住院的患者由于疾病对大脑的影响以及患病带来的心理社会压力,存在发生多种神经精神障碍的风险。本研究旨在评估因 COVID-19 住院并接受精神科会诊的患者的特征和结局。回顾性分析了因 COVID-19 住院的 892 例患者和其中 89 例要求精神科会诊的患者的病历。在精神科会诊后,患者最常被诊断为谵妄(38.2%)、适应障碍(27.0%)、抑郁障碍(19.1%)和焦虑障碍(11.2%)。谵妄患者的住院时间更长(p<0.001)、更频繁地转至重症监护病房(p<0.001)、住院期间死亡率更高(p<0.001),均显著高于其他患者。谵妄患者以及接受其他精神科诊断的患者需要吸氧(p<0.001)和机械通气(p<0.001)的比例也明显更高。COVID-19 病房住院患者存在神经精神障碍,这些障碍会对 COVID-19 的预后产生负面影响。我们的研究结果表明,COVID-19 住院患者存在神经精神障碍可能与疾病的不良结局有关。