Kulairi Zain, Deol Nisha, Tolly Renee, Manocha Rohan, Naseer Maliha
Department of Internal Medicine, Crittenton Hospital Medical Center, Wayne State University, Rochester, MI 48307, USA.
Case Rep Cardiol. 2017;2017:7612748. doi: 10.1155/2017/7612748. Epub 2017 Jan 5.
Hyperthyroidism is a highly prevalent disease affecting over 4 million people in the US. The disease is associated with many cardiac complications including atrial fibrillation and also less commonly with ventricular tachycardia and fibrillation. Many cardiac pathologies have been extensively studied; however, the relationship between hyperthyroidism and rate of ventricular repolarization manifesting as a prolonged QTc interval is not well known. Prolonged QTc interval regardless of thyroid status is a risk factor for cardiovascular mortality and life-threatening ventricular arrhythmia. The mechanism regarding the prolongation of the QT interval in a hyperthyroid patient has not been extensively investigated although its clinical implications are relevant. Herein, we describe a case of prolonged QTc in a patient who presented with signs of hyperthyroidism that was corrected with return to euthyroid status.
甲状腺功能亢进症是一种高发疾病，在美国影响着超过400万人。该疾病与许多心脏并发症相关，包括心房颤动，较少见的还有室性心动过速和心室颤动。许多心脏病理情况已得到广泛研究；然而，甲状腺功能亢进症与表现为QTc间期延长的心室复极速率之间的关系尚不清楚。无论甲状腺状态如何，QTc间期延长都是心血管死亡和危及生命的室性心律失常的危险因素。尽管甲状腺功能亢进症患者QT间期延长的临床意义重大，但其延长机制尚未得到广泛研究。在此，我们描述一例出现甲状腺功能亢进症体征的患者QTc延长的病例，该病例在恢复甲状腺功能正常状态后得到纠正。
