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[儿童尿路感染]

[Urinary tract infections in children].

作者信息

Lellig E, Apfelbeck M, Straub J, Karl A, Tritschler S, Stief C G, Riccabona M

机构信息

Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

出版信息

Urologe A. 2017 Feb;56(2):247-262. doi: 10.1007/s00120-016-0316-x.

DOI:10.1007/s00120-016-0316-x
PMID:28154883
Abstract

Urinary tract infections (UTI) are the most common bacterial infections in children. The symptoms are not very specific and range from abdominal pain, poor feeding to nocturnal urinary incontinence. The technique of collecting urine plays an important role for securing the diagnosis. The best way to obtain urine in non-toilet-trained children is catheterization or suprapubic bladder aspiration. In toilet-trained children midstream urine is an acceptable alternative after cleaning the foreskin or labia. In the case of an infection a prompt empirical antibiotic therapy is necessary to reduce the risk of parenchymal scarring of the kidneys. There are different approaches to diagnose vesicoureteral reflux in different countries. The commonly used standard approach in Germany is voiding cystourethrography. In the case of reflux dimercaptosuccinic acid (DMSA) scintigraphy should be performed additionally to exclude renal scarring (bottom-up approach).

摘要

尿路感染(UTI)是儿童最常见的细菌感染。其症状不太具有特异性,范围从腹痛、喂养不良到夜间尿失禁。尿液采集技术对确诊起着重要作用。对于未接受如厕训练的儿童,获取尿液的最佳方法是导尿或耻骨上膀胱穿刺抽吸。对于已接受如厕训练的儿童,清洁包皮或阴唇后,中段尿是一种可接受的替代方法。在发生感染的情况下,及时进行经验性抗生素治疗对于降低肾脏实质瘢痕形成的风险是必要的。不同国家诊断膀胱输尿管反流有不同的方法。德国常用的标准方法是排尿性膀胱尿道造影。对于反流情况,应额外进行二巯基丁二酸(DMSA)肾闪烁扫描以排除肾瘢痕形成(自下而上的方法)。

相似文献

1
[Urinary tract infections in children].[儿童尿路感染]
Urologe A. 2017 Feb;56(2):247-262. doi: 10.1007/s00120-016-0316-x.
2
The method of urine sampling is not a valid predictor for vesicoureteral reflux in children after febrile urinary tract infections.尿液采样方法并非预测发热性尿路感染后儿童膀胱输尿管反流的有效指标。
J Pediatr Urol. 2017 Oct;13(5):500.e1-500.e5. doi: 10.1016/j.jpurol.2017.01.025. Epub 2017 Mar 16.
3
Impact of micturating cystourethrography and DMSA renal scintigraphy on the investigation scheme in children with urinary tract infection.排尿性膀胱尿道造影和二巯基丁二酸肾闪烁扫描对尿路感染患儿检查方案的影响。
Ann Nucl Med. 2008 Oct;22(8):661-5. doi: 10.1007/s12149-008-0178-4. Epub 2008 Nov 4.
4
Alternative approaches to the prognostic stratification of mild to moderate primary vesicoureteral reflux in children.儿童轻至中度原发性膀胱输尿管反流预后分层的替代方法。
J Urol. 1996 Jun;155(6):2052-5; discussion 2055-6.
5
Resistive index in febrile urinary tract infections: predictive value of renal outcome.发热性尿路感染中的阻力指数:对肾脏预后的预测价值。
Pediatr Nephrol. 2004 Feb;19(2):148-52. doi: 10.1007/s00467-003-1305-z. Epub 2003 Dec 18.
6
Urinary tract infections in children: EAU/ESPU guidelines.儿童尿路感染:EAU/ESPU 指南。
Eur Urol. 2015 Mar;67(3):546-58. doi: 10.1016/j.eururo.2014.11.007. Epub 2014 Dec 2.
7
Urinary tract infection in infants: the significance of low bacterial count.婴儿尿路感染:低细菌计数的意义
Pediatr Nephrol. 2016 Feb;31(2):239-45. doi: 10.1007/s00467-015-3199-y. Epub 2015 Sep 10.
8
A midstream urine collector is not a good alternative to a sterile collection method during the diagnosis of urinary tract infection.在尿路感染诊断过程中,中段尿收集器并非无菌收集方法的良好替代方案。
Acta Paediatr. 2015 Sep;104(9):e395-400. doi: 10.1111/apa.13019. Epub 2015 May 4.
9
[Procalcitonin, a useful biomarker in pediatric urinary tract infection].[降钙素原,儿童尿路感染中的一种有用生物标志物]
Arch Pediatr. 2013 Jan;20(1):54-62. doi: 10.1016/j.arcped.2012.10.025. Epub 2012 Nov 27.
10
The relation of vesicoureteral reflux and renal scarring in childhood urinary tract infection.儿童尿路感染中膀胱输尿管反流与肾瘢痕形成的关系。
J Med Assoc Thai. 2006 Aug;89 Suppl 2:S41-7.

本文引用的文献

1
Early Antibiotic Treatment for Pediatric Febrile Urinary Tract Infection and Renal Scarring.儿科发热性尿路感染和肾瘢痕的早期抗生素治疗。
JAMA Pediatr. 2016 Sep 1;170(9):848-54. doi: 10.1001/jamapediatrics.2016.1181.
2
Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis.全球大肠杆菌引起的小儿尿路感染的抗生素耐药性患病率及其与基层医疗中抗生素常规使用的关联:系统评价与荟萃分析
BMJ. 2016 Mar 15;352:i939. doi: 10.1136/bmj.i939.
3
Probiotics for preventing urinary tract infections in adults and children.
用于预防成人和儿童尿路感染的益生菌。
Cochrane Database Syst Rev. 2015 Dec 23;2015(12):CD008772. doi: 10.1002/14651858.CD008772.pub2.
4
Risk Factors for Recurrent Urinary Tract Infection and Renal Scarring.复发性尿路感染和肾瘢痕形成的危险因素。
Pediatrics. 2015 Jul;136(1):e13-21. doi: 10.1542/peds.2015-0409. Epub 2015 Jun 8.
5
Does prompt treatment of urinary tract infection in preschool children prevent renal scarring: mixed retrospective and prospective audits.学龄前儿童尿路感染的及时治疗是否能预防肾瘢痕形成:混合回顾性和前瞻性审计。
Arch Dis Child. 2014 Apr;99(4):342-7. doi: 10.1136/archdischild-2013-304428. Epub 2013 Dec 18.
6
Antibiotic resistance patterns of outpatient pediatric urinary tract infections.门诊小儿尿路感染的抗生素耐药模式。
J Urol. 2013 Jul;190(1):222-7. doi: 10.1016/j.juro.2013.01.069. Epub 2013 Jan 28.
7
[Diagnostics and therapy of urinary tract infections].[尿路感染的诊断与治疗]
Urologe A. 2013 Jan;52(1):21-2, 24-8, 30-2. doi: 10.1007/s00120-012-3078-0.
8
Positioning irrigation of contrast cystography for diagnosis of occult vesicoureteric reflux: association with technetium-99m dimercaptosuccinic acid scans.对比性膀胱造影术定位灌洗诊断隐匿性膀胱输尿管反流:与锝 99m 二巯丁二酸扫描的相关性。
J Pediatr Urol. 2013 Dec;9(6 Pt A):846-50. doi: 10.1016/j.jpurol.2012.11.010. Epub 2012 Dec 5.
9
Cranberries for preventing urinary tract infections.蔓越莓预防尿路感染。
Cochrane Database Syst Rev. 2012 Oct 17;10(10):CD001321. doi: 10.1002/14651858.CD001321.pub5.
10
Contamination rates of different urine collection methods for the diagnosis of urinary tract infections in young children: an observational cohort study.不同尿液采集方法用于幼儿尿路感染诊断的污染率:一项观察性队列研究
J Paediatr Child Health. 2012 Aug;48(8):659-64. doi: 10.1111/j.1440-1754.2012.02449.x. Epub 2012 Apr 27.