Savchenko A P, Frolova M I, Zharov I N, Samko A N, Pomerantsev E V
Vestn Rentgenol Radiol. 1989 Jul-Aug(4):13-6.
Altogether 30 patients with unstable angina (UA) were examined. In 15 patients omnipaque was used during coronography and ventriculography (VG), in the rest of 15 patients--verografin at common dosages. A study was made of the changes in the indices of central hemodynamics and myocardial contractility resulting from the action of these radiopaque media during VG, and of ECG changes during coronography. VG with verografin was accompanied by more noticeable disorders of left ventricular contractility, an increase in myocardial oxygen consumption; coronography with omnipaque was characterized by later ECG changes, less noticeable disorders of intraventricular conductivity. It is advisable that coronaroventriculography in patients with UA should be performed using a new group of radiopaque media, in particular omnipaque.
共对30例不稳定型心绞痛(UA)患者进行了检查。15例患者在冠状动脉造影和心室造影(VG)期间使用了碘海醇,其余15例患者使用了常规剂量的泛影葡胺。研究了这些造影剂在VG期间作用导致的中心血流动力学指标和心肌收缩性变化,以及冠状动脉造影期间的心电图变化。使用泛影葡胺进行VG时,左心室收缩性紊乱更明显,心肌耗氧量增加;使用碘海醇进行冠状动脉造影时,心电图变化出现较晚,室内传导紊乱不太明显。建议UA患者进行冠状动脉心室造影时应使用一组新的造影剂,尤其是碘海醇。