细胞学异常的孕妇人群中宫颈上皮内瘤变的发病率。
The incidence of cervical intraepithelial neoplasia in a population of pregnant women with an abnormal cytology.
作者信息
Pruski Dominik, Malkowska-Walczak Blanka, Paluszkiewicz Aleksandra, Kędzia Witold
机构信息
Division of Gynecology, Department of Perinatology and Gynecology, Gynecology and Obstetrics Clinical Hospital, Karol Marcinkowski University of Medical Sciences, Poznan, Poland Laboratory of Pathophysiology of Uterine Cervix, Gynecology and Obstetrics Clinical Hospital, Karol Marcinkowski University of Medical Sciences, Poznan, Poland.
出版信息
Ginekol Pol. 2017;88(1):20-23. doi: 10.5603/GP.a2017.0004.
OBJECTIVES
To assess the incidence of cervical intraepithelial neoplasia - SIL and cervical cancer in a population of pregnant women with an abnormal cytology.
MATERIAL AND METHODS
In pregnant women with abnormal cytology results according to The Bethesda System, a verifying diagnostics was carried out, including colposcopy and cervical biopsy.
RESULTS
The most common histological and oncologic diagnosis in the whole study group of pregnant women were HGSIL changes, covering cervical intraepithelial neoplasia of medium and high grade - CIN 2 and CIN 3.
CONCLUSIONS
HGSIL changes are the most common oncological pathology in a population of pregnant women with an abnormal cytology. Precise risk identification of HGSIL changes with the use of molecular tests can significantly reduce the number of surgical procedures in a population of pregnant patients with a cytological diagnosis of ASCUS and LSIL.
目的
评估细胞学异常的孕妇人群中宫颈上皮内瘤变（SIL）和宫颈癌的发病率。
材料与方法
对于根据贝塞斯达系统细胞学结果异常的孕妇，进行了包括阴道镜检查和宫颈活检在内的确诊诊断。
结果
整个孕妇研究组中最常见的组织学和肿瘤学诊断为高级别鳞状上皮内病变（HGSIL）改变，涵盖中高级别宫颈上皮内瘤变（CIN 2和CIN 3）。
结论
HGSIL改变是细胞学异常的孕妇人群中最常见的肿瘤病理。使用分子检测精确识别HGSIL改变的风险可显著减少细胞学诊断为非典型鳞状细胞不能明确意义（ASCUS）和低级别鳞状上皮内病变（LSIL）的孕妇患者的手术数量。
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