Zidkova Monika, Hlozek Tomas, Balik Martin, Kopecky Ondrej, Tesinsky Pavel, Svanda Jan, Balikova Marie Anna
Institute Forensic Medicine and Toxicology, First Faculty of Medicine, Charles University and General University Hospital, Ke Karlovu 2, Prague 2, Prague.
Department of Anaesthesiology, Resuscitation and Intensive Medicine, First Faculty of Medicine, Charles University and General University Hospital, U Nemocnice 2, Prague 2, Prague.
J Anal Toxicol. 2017 May 1;41(4):350-354. doi: 10.1093/jat/bkx009.
3-Methoxy-phencyclidine (3-MeO-PCP) is a structural derivative of the dissociative hallucinogen phencyclidine (PCP). Although PCP toxicity is well documented, little is known about this new psychoactive substance despite being available on the black market even in central Europe. The objective of this case report is to present clinical and laboratory data of analytically confirmed non-fatal intoxication of two subjects with 3-MeO-PCP. A preliminary assessment of potential metabolites excreted into urine was enabled using the liquid chromatography high resolution mass spectrometric method.
3-甲氧基-苯环己哌啶（3-MeO-PCP）是分离性致幻剂苯环己哌啶（PCP）的结构衍生物。尽管PCP的毒性已有充分记录，但这种新的精神活性物质尽管在中欧的黑市上也有销售，却鲜为人知。本病例报告的目的是呈现两例经分析确认的3-MeO-PCP非致命中毒患者的临床和实验室数据。使用液相色谱高分辨率质谱法对尿液中排泄的潜在代谢物进行了初步评估。
