Larvate depressions (LD) are a particular type of significance of endogenic depressions. 2. Somatic-vegetative symptoms are mostly uppermost and involve the risk of diagnostic and therapeutic errors. Therefore it is particularly to be thought of the diagnosis of a larvate depression in non-psychiatric subjects. 3. Diagnostically decisive is the comprehension of the discretely existing endomorphous cyclothymic fundamental syndrome. 4. The therapy is that of the endogenic depression. Essential fundaments are the administration of psychopharmacologic agents, particularly tricyclic antidepressive drugs, the consequent psychic management of the patients, at the beginning emphasized in the sense of tranquilizing assurances and the consideration of social points of view.