Luther H, Banas J, Daweke-Pickardt G, Hoffmann K, Fabry H, Altmeyer P
Dermatologische Klinik, Ruhr-Universität Bochum.
Z Hautkr. 1989 Sep 15;64(9):748-50, 753-5.
Cryosurgery is considered an alternative method in the treatment of basal cell carcinomas of the face and usually leads to excellent functional and cosmetic results. This technique can be modified depending on the number of freeze-thaw cycles. According to our experiences (220 cases), a single freeze-thaw cycle is indicated for those basal cell carcinomas which do not go beyond the middle dermis; these cases were characterized by fast wound healing and a very satisfying cosmetic outcome. Invasion of the lower dermis as well as basal cell carcinomas in skin folds require repeated freeze-thaw cycles. The specific mode of cryosurgical treatment, therefore, has to be differentiated depending on the site of the tumor and its depth of invasion.
冷冻手术被认为是治疗面部基底细胞癌的一种替代方法，通常能带来出色的功能和美容效果。该技术可根据冻融循环次数进行调整。根据我们的经验（220例），对于未超出真皮中层的基底细胞癌，单次冻融循环即可；这些病例的特点是伤口愈合快，美容效果非常令人满意。真皮下层受侵以及皮肤褶皱处的基底细胞癌则需要重复冻融循环。因此，冷冻手术的具体治疗方式必须根据肿瘤部位及其浸润深度加以区分。
