Birri Marcela, Vallejo Mariana, Carro-Juárez Miguel, Agnese A Mariel
IMBIV, CONICET and Farmacognosia, Departamento de Farmacia, Fac. de Ciencias Químicas, Universidad Nacional de Córdoba, X5000HUA Córdoba, Argentina.
Laboratorio de Comportamiento Reproductivo, Escuela de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Tlaxcala, C.P.90000, Col. Centro, Tlaxcala, México.
Phytomedicine. 2017 Jan 15;24:104-110. doi: 10.1016/j.phymed.2016.11.020. Epub 2016 Nov 30.
Phlegmariurus saururus is popularly known in Argentina as aphrodisiac. For this reason, it was previously investigated and determined that the decoction of this plant elicits pro-ejaculatory activity and increases the ejaculatory potency in the Fictive Ejaculation Model. HYPOTHESIS/PURPOSE: the decoction of P. saururus facilitates sexual behavior in sexually experienced male rat and induces copulatory behavior in non-copulating male rats.
The extraction method (decoction) was validated through Selectivity, Accuracy and Precision, by identification of the majority alkaloids, expressed as sauroxine. Male (sexually experienced and noncopulating) and female (receptive) Wistar rats were used to determine sexual behavior. Sildenafil was used as positive control. The following variables were evaluated: Mount Latency, Intromission Latency, Ejaculation Latency, Post Ejaculatory Interval, as well as the Mounts and Intromissions Number.
In sexually experienced male rats, P. saururus decoction stimulates sexual arousal and facilitates sexual execution. In noncopulating male rats, this decoction induces copulation with behavioral characteristics similar to sexually experienced animals.
P. saururus possesses aphrodisiac activity in copulating and noncopulating male rats.
在阿根廷，龙须石杉作为一种壮阳药广为人知。因此，此前曾对其进行研究并确定，在假射精模型中，这种植物的煎剂具有促进射精的活性，并能提高射精能力。
假设/目的：龙须石杉煎剂可促进有性经验雄性大鼠的性行为，并诱导未交配雄性大鼠的交配行为。
通过选择性、准确性和精密度，通过鉴定以石杉碱表示的主要生物碱，对提取方法（煎剂）进行了验证。使用雄性（有性经验和未交配）和雌性（处于接受期）Wistar大鼠来确定性行为。使用西地那非作为阳性对照。评估以下变量：爬跨潜伏期、插入潜伏期、射精潜伏期、射精后间隔时间，以及爬跨次数和插入次数。
在有性经验的雄性大鼠中，龙须石杉煎剂刺激性唤起并促进性行为。在未交配的雄性大鼠中，这种煎剂诱导其交配，且行为特征与有性经验的动物相似。
龙须石杉在交配和未交配的雄性大鼠中均具有壮阳活性。
