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紫铆提取物对雄性大鼠的壮阳活性。

Aphrodisiac activity of Butea frondosa Koen. ex Roxb. extract in male rats.

作者信息

Ramachandran S, Sridhar Y, Sam S Kishore Gnana, Saravanan M, Leonard J Thomas, Anbalagan N, Sridhar S K

机构信息

Department of Pharmacology and Toxicology, C. L. Baid Metha College of Pharmacy, Thorapakkam, Old Mahabalipuram Road, Chennai, India.

出版信息

Phytomedicine. 2004 Feb;11(2-3):165-8. doi: 10.1078/0944-7113-00343.

Abstract

In the present study, the aphrodisiac activity of Butea frondonsa Koen. ex Roxb (Papillionaceae) bark extract was investigated. The extract (400 mg/kg body wt./day) was administered orally by gavage for 28 days. Mount latency (ML), intromission latency (IL), ejaculation latency (EL), mounting frequency (MF), intromission frequency (IF), ejaculation frequency (EF) and post-ejaculatory interval (PEI) were the parameters observed before and during the sexual behavior study at day 0, 7, 10, 14, 21, and 28. The extract reduced significantly ML, IL, EL and PEI (p < 0.05). The extract also increased significantly MF, IF and EF (p < 0.05). These effects were observed in sexually active and inactive male rats.

摘要

在本研究中,对紫铆(豆科)树皮提取物的壮阳活性进行了研究。提取物(400毫克/千克体重/天)通过灌胃法口服给药28天。在性行为研究的第0、7、10、14、21和28天,观察爬跨潜伏期(ML)、插入潜伏期(IL)、射精潜伏期(EL)、爬跨频率(MF)、插入频率(IF)、射精频率(EF)和射精后间隔时间(PEI)等参数。提取物显著降低了ML、IL、EL和PEI(p<0.05)。提取物还显著提高了MF、IF和EF(p<0.05)。在性活跃和性不活跃的雄性大鼠中均观察到了这些作用。

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