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光学相干断层扫描技术下脉络膜巩膜界面形态的过去、现在和未来概念

Past, Present, and Future Concepts of the Choroidal Scleral Interface Morphology on Optical Coherence Tomography.

作者信息

Huynh Emily, Chandrasekera Erandi, Bukowska Danuta, McLenachan Samuel, Mackey David A, Chen Fred K

机构信息

Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Australia.

Lions Eye Institute, Perth, Australia.

出版信息

Asia Pac J Ophthalmol (Phila). 2017 Jan-Feb;6(1):94-103. doi: 10.22608/APO.201698.

DOI:10.22608/APO.201698
PMID:28161920
Abstract

The choroid is the most vascular tissue in the eye and it has been implicated in the pathophysiology of a variety of ocular diseases. A new era of research in the choroid began with the improved ability to visualize this layer and its inner and outer boundaries using spectral domain optical coherence tomography (OCT) with enhanced depth imaging and swept source OCT. The accuracy and precision of qualitative and quan-titative assessments of the choroidal layer support the potential use of OCT-derived choroidal parameters for diagnosis, monitoring of disease progression, planning surgical access, and evaluating treatment response. Although there is increasing interest in measuring choroidal thickness, there is currently no consensus nomenclature to classify choroidal layers and boundaries. Furthermore, the definition and description of the choroidal scleral interface is inconsistent in the literature, contributing to interstudy variation in choroidal thickness measurements. The purpose of this review is to provide an overview of the literature on the definition of choroidal layers and choroidal scleral boundary, review the discrepan-cies, and harmonize the terminology so that a consensus nomenclature can be proposed.

摘要

脉络膜是眼部血管最丰富的组织,它与多种眼部疾病的病理生理学有关。随着使用具有增强深度成像功能的光谱域光学相干断层扫描(OCT)和扫频源OCT可视化该层及其内外边界的能力得到提高,脉络膜研究进入了一个新时代。对脉络膜层进行定性和定量评估的准确性和精确性支持将OCT衍生的脉络膜参数用于诊断、监测疾病进展、规划手术入路以及评估治疗反应。尽管测量脉络膜厚度的兴趣日益增加,但目前尚无对脉络膜层和边界进行分类的统一命名法。此外,脉络膜巩膜界面的定义和描述在文献中并不一致,这导致了脉络膜厚度测量研究间的差异。本综述的目的是概述关于脉络膜层定义和脉络膜巩膜边界的文献,回顾差异,并统一术语,以便提出统一的命名法。

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