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增强深度成像在扫频源光学相干断层扫描中的应用:提高脉络膜和巩膜的可视性,一项掩蔽研究。

Enhanced depth imaging in swept-source optical coherence tomography: Improving visibility of choroid and sclera, a masked study.

机构信息

Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, Israel.

Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

出版信息

Eur J Ophthalmol. 2020 Nov;30(6):1295-1300. doi: 10.1177/1120672119863560. Epub 2019 Jul 26.

Abstract

PURPOSE

To compare enhanced depth imaging in swept-source optical coherence tomography and non-enhanced depth imaging optical coherence tomography in their ability to capture choroidal and scleral details.

METHODS

Averaged foveal B-Scans were obtained from 40 eyes of 20 healthy volunteers by swept-source optical coherence tomography with and without enhanced depth imaging. Visibility and contrast of vascular details within the choroid, choroidoscleral junction, and sclera were evaluated by masked readers using an ordinal scoring scale. Outcomes were analyzed using the Wilcoxon signed rank-sum test.

RESULTS

Visibility of the choroidal vascular details ( = 5.94,  < .001), the choroidoscleral junction ( = 5.85,  < .001), and the sclera ( = 6.80,  < .001) was significantly higher with enhanced depth imaging than with non-enhanced depth imaging swept-source optical coherence tomography. Similarly, image contrast was significantly higher with enhanced depth imaging than with non-enhanced depth imaging swept-source optical coherence tomography for the choroidal vascular details ( = 9.47,  < .001), for the choroidoscleral junction ( = 9.28,  < .001), and for the sclera ( = 9.42,  < .001).

CONCLUSION

Enhanced depth imaging applied to swept-source optical coherence tomography-averaged foveal B-scans enhances visualization of the choroidal details, of the choroidoscleral junction, and of the sclera. This novel modality can easily be implemented in clinics and could improve our understanding of conditions involving the choroid or the sclera.

摘要

目的

比较增强深度成像在扫频源光相干断层扫描和非增强深度成像光相干断层扫描在捕捉脉络膜和巩膜细节方面的能力。

方法

通过扫频源光相干断层扫描获得 20 名健康志愿者 40 只眼的平均中心凹 B 扫描,分别采用增强深度成像和非增强深度成像。通过掩蔽阅读器使用有序评分量表评估脉络膜、脉络膜巩膜交界处和巩膜内血管细节的可见度和对比度。使用 Wilcoxon 符号秩和检验分析结果。

结果

增强深度成像的脉络膜血管细节(=5.94,<0.001)、脉络膜巩膜交界处(=5.85,<0.001)和巩膜(=6.80,<0.001)的可见度明显高于非增强深度成像扫频源光相干断层扫描。同样,增强深度成像的图像对比度明显高于非增强深度成像扫频源光相干断层扫描,用于脉络膜血管细节(=9.47,<0.001)、脉络膜巩膜交界处(=9.28,<0.001)和巩膜(=9.42,<0.001)。

结论

增强深度成像应用于扫频源光相干断层扫描平均中心凹 B 扫描可增强脉络膜细节、脉络膜巩膜交界处和巩膜的可视化。这种新的模式可以很容易地在临床上实施,并可以提高我们对涉及脉络膜或巩膜的疾病的理解。

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