Whitehead H M, Gilliland J S, Allen I V, Hadden D R
Sir George E. Clark Metabolic Unit, Royal Victoria Hospital, Belfast, Northern Ireland, UK.
Acta Paediatr Scand Suppl. 1989;356:65-7; discussion 68, 73-4. doi: 10.1111/j.1651-2227.1989.tb11246.x.
The effect of a 6-month period of substitution therapy with recombinant human growth hormone (rhGH) on muscle fibre size and muscle fibre type proportions has been investigated in a group of 13 adults with growth hormone deficiency. All had a peak growth hormone (GH) response to insulin-induced hypoglycaemia of less than 7 mU/l. There was no statistically significant change in the lesser fibre diameter or fibre proportions of either type 1 or type 2 muscle fibres in the rhGH group, as compared with placebo.
在一组13名生长激素缺乏的成年人中，研究了为期6个月的重组人生长激素（rhGH）替代疗法对肌纤维大小和肌纤维类型比例的影响。所有人对胰岛素诱导的低血糖的生长激素（GH）峰值反应均低于7 mU/l。与安慰剂相比，rhGH组中1型或2型肌纤维的较小纤维直径或纤维比例没有统计学上的显著变化。
