Okusanya Babasola O, Oduwole Olabisi, Nwachuku Nuria, Meremikwu Martin M
Experimental and Maternal Medicine Unit, Department of Obstetrics and Gynecology, Faculty of Clinical Sciences, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria.
Institute of Tropical Diseases Research and Prevention, University of Calabar Teaching Hospital, Calabar, Nigeria.
Int J Gynaecol Obstet. 2017 Feb;136 Suppl 1:13-20. doi: 10.1002/ijgo.12056.
Deinfibulation is a surgical procedure carried out to re-open the vaginal introitus of women living with type III female genital mutilation (FGM).
To assess the impact of deinfibulation on gynecologic or obstetric outcomes by comparing women who were deinfibulated with women with type III FGM or women without FGM.
Major databases including CENTRAL, MEDLINE, and Scopus were searched until August 2015.
We included nonrandomized studies that compared obstetric outcomes of women with deinfibulation, type III FGM (not deinfibulated during labor), and no FGM.
Quality of evidence was determined following the GRADE methodology. Summary measures were calculated using odds ratios at 95% confidence intervals.
We found no randomized controlled trials. We included four case-control studies. The quality of evidence was very low. Compared with women with type III FGM at delivery, deinfibulated women had a significant reduction in the risk of having a cesarean delivery or postpartum hemorrhage. Compared with women without FGM, deinfibulated women had a similar risk of episiotomy, cesarean delivery, vaginal lacerations, postpartum hemorrhage, and blood loss at vaginal delivery. The length of second stage of labor, mean maternal hospital stay, and Apgar scores less than 7 were also comparable.
Low-quality evidence suggests deinfibulation improves birth outcomes for women with type III FGM.
CRD42015024466.
阴蒂切开术修复是一种外科手术,用于为患有III型女性生殖器切割(FGM)的女性重新打开阴道入口。
通过比较接受阴蒂切开术修复的女性与患有III型FGM的女性或未接受FGM的女性,评估阴蒂切开术修复对妇科或产科结局的影响。
检索了包括CENTRAL、MEDLINE和Scopus在内的主要数据库,直至2015年8月。
我们纳入了比较接受阴蒂切开术修复的女性、III型FGM(分娩时未进行修复)的女性和未接受FGM的女性产科结局的非随机研究。
根据GRADE方法确定证据质量。使用95%置信区间的比值比计算汇总指标。
我们未找到随机对照试验。我们纳入了四项病例对照研究。证据质量非常低。与分娩时患有III型FGM的女性相比,接受阴蒂切开术修复的女性剖宫产或产后出血的风险显著降低。与未接受FGM的女性相比,接受阴蒂切开术修复的女性会阴切开术、剖宫产、阴道撕裂伤、产后出血和阴道分娩时失血的风险相似。第二产程长度、产妇平均住院时间和Apgar评分低于7分的情况也相当。
低质量证据表明阴蒂切开术修复可改善患有III型FGM女性的分娩结局。
PROSPERO注册编号:CRD42015024466。