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钕钇铝石榴石激光与强脉冲光系统脱毛疗效及副作用比较(18个月随访)

Comparison of hair removal efficacy and side effect of neodymium:Yttrium-aluminum-garnet laser and intense pulsed light systems (18-month follow-up).

作者信息

Szima Georgina Zita, Janka Eszter Anna, Kovács Anikó, Bortély Blanka, Bodnár Edina, Sawhney Irina, Szabó Éva, Remenyik Éva

机构信息

Department of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

出版信息

J Cosmet Dermatol. 2017 Jun;16(2):193-198. doi: 10.1111/jocd.12312. Epub 2017 Feb 6.

Abstract

BACKGROUND

Photothermal destruction of hair shaft melanin with intense pulsed light (IPL) and neodymium:yttrium-aluminum-garnet (Nd:YAG) laser has become an effective treatment of hair removal.

AIMS

Our aim was to compare efficacy, satisfactory levels, safety, and side effects of Nd:YAG and IPL in hair reduction.

METHODS

This was a prospective randomized intrapatient, right-left, assessor-blinded comparison of Nd:YAG vs IPL. There were 38 volunteers recruited. Seven sessions were performed. Hair count, efficacy, and side effects were compared before and after each treatment and 6 months after the last treatment. In respect of 12 volunteers, we have examined the reduction in hair after 18 months.

RESULTS

Initially, there was no significant difference between the numbers of hair follicles. There was significant hair reduction after each treatment on the Nd:YAG-treated side. The hair reduction became significant after the third treatment with IPL. Comparison of the efficacy of the two devices on each visits showed no significant difference. There was statistically lower pain score on the IPL-treated side and statistically higher erythema, burning sensation, and edema on the Nd:YAG-treated side. Statistically lower side effect score was observed on the IPL-treated side. Eight months after the last treatment, there was significant hair reduction both on the Nd:YAG and on the IPL-treated side, and there was no difference between the efficacy. The patient satisfaction scores were higher with the IPL.

CONCLUSION

Unwanted hair can be reduced by both systems safely and effectively; however, IPL has less side effects and higher satisfaction scores.

摘要

背景

强脉冲光(IPL)和钕:钇铝石榴石(Nd:YAG)激光对毛干黑色素进行光热破坏已成为一种有效的脱毛治疗方法。

目的

我们的目的是比较Nd:YAG和IPL在减少毛发方面的疗效、满意度、安全性和副作用。

方法

这是一项前瞻性随机患者内左右侧评估者盲法比较Nd:YAG与IPL的研究。招募了38名志愿者。进行了7次治疗。在每次治疗前后以及最后一次治疗后6个月比较毛发计数、疗效和副作用。对于12名志愿者,我们检查了18个月后的毛发减少情况。

结果

最初,毛囊数量之间没有显著差异。Nd:YAG治疗侧每次治疗后毛发均有显著减少。IPL第三次治疗后毛发减少变得显著。每次就诊时两种设备疗效的比较显示无显著差异。IPL治疗侧的疼痛评分在统计学上较低,Nd:YAG治疗侧的红斑、烧灼感和水肿在统计学上较高。IPL治疗侧的副作用评分在统计学上较低。最后一次治疗8个月后,Nd:YAG和IPL治疗侧的毛发均有显著减少,且疗效无差异。IPL的患者满意度评分更高。

结论

两种系统均可安全有效地减少多余毛发;然而,IPL的副作用更少,满意度评分更高。

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