Zhou Qi, Zhang Tianjiao, Ren Simei, Li Xiaopeng, Hu Jihong, Li Shaonan, Gao Zhenxiang
Clin Lab. 2016 Oct 1;62(10):2053-2056. doi: 10.7754/Clin.Lab.2016.160227.
In EQA schemes, results are usually assessed against a target value.
Outliers in each result were deleted using a robust statistical method. Mean was used as a target value if trimmed results were normally distributed; otherwise, median was used. Differences between target value and Roche's calibration value were calculated. Rates of acceptable performance evaluated by target value and Roche's calibration value were determined.
Target values of P, GLU, urea, UA, TP, ALB, TC, TG, ALT, AST, ALP, AMY, LDH, GGT, FE, and HBDH were 1.70 mmol/L, 11.0 mmol/L, 16.8 mmol/L, 307 μmol/L, 54.0 g/L, 38.1 g/L, 4.19 mmol/L, 1.46 mmol/L, 97.7 U/L, 98.2 U/L, 206 U/L, 180 U/L, 242 U/L, 115 U/L, 35.6 μmol/L, and 255 U/L, respectively. Differences between target values and Roche's calibration values were -3.45 to 1.48%. Rates of acceptable performance evaluated by target values and Roche's calibration values were 96.5 - 100.0% and 93.0 - 100.0%, respectively.
Target values established using a robust statistical method and Roche's calibration values were comparable.
在室间质量评价计划中，结果通常根据目标值进行评估。
使用稳健的统计方法删除每个结果中的离群值。如果剔除后的结果呈正态分布，则使用均值作为目标值；否则，使用中位数。计算目标值与罗氏校准值之间的差异。确定通过目标值和罗氏校准值评估的可接受性能率。
磷（P）、葡萄糖（GLU）、尿素、尿酸（UA）、总蛋白（TP）、白蛋白（ALB）、总胆固醇（TC）、甘油三酯（TG）、谷丙转氨酶（ALT）、谷草转氨酶（AST）、碱性磷酸酶（ALP）、淀粉酶（AMY）、乳酸脱氢酶（LDH）、γ-谷氨酰转肽酶（GGT）、铁（FE）和α-羟丁酸脱氢酶（HBDH）的目标值分别为1.70毫摩尔/升、11.0毫摩尔/升、16.8毫摩尔/升、307微摩尔/升、54.0克/升、38.1克/升、4.19毫摩尔/升、1.46毫摩尔/升、97.7单位/升、98.单位/升、206单位/升、180单位/升、242单位/升、115单位/升、35.6微摩尔/升和255单位/升。目标值与罗氏校准值之间的差异为-3.45%至1.48%。通过目标值和罗氏校准值评估的可接受性能率分别为96.5%至100.0%和93.0%至100.0%。
使用稳健统计方法确定的目标值与罗氏校准值具有可比性。
