Murtaza Nida, Ó Cuív Páraic, Morrison Mark
The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, Queensland 4102, Australia.
The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, Queensland 4102, Australia.
Gastroenterol Clin North Am. 2017 Mar;46(1):49-60. doi: 10.1016/j.gtc.2016.09.005. Epub 2017 Jan 4.
The gut microbiota provides a range of ecologic, metabolic, and immunomodulatory functions relevant to health and well-being. The gut microbiota not only responds quickly to changes in diet, but this dynamic equilibrium may be managed to prevent and/or treat acute and chronic diseases. This article provides a working definition of the term "microbiome" and uses two examples of dietary interventions for the treatment of large bowel conditions to emphasize the links between diet and microbiome. There remains a need to develop a better functional understanding of the microbiota, if its management for clinical utility is to be fully realized.
肠道微生物群提供了一系列与健康和幸福相关的生态、代谢及免疫调节功能。肠道微生物群不仅对饮食变化反应迅速,而且这种动态平衡可以加以调控以预防和/或治疗急慢性疾病。本文给出了“微生物组”一词的实用定义,并通过两个饮食干预治疗大肠疾病的例子来强调饮食与微生物组之间的联系。如果要充分实现对微生物群的临床应用管理,仍需要对其功能有更深入的了解。