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应激性胃溃疡:以新生儿大量直肠出血为表现

Stress Induced Gastric Ulcers: Presenting as Massive Rectal Bleeding in a Newborn.

作者信息

Joshi A, Shrestha P S, Dangol S, Shrestha N C, Poudyal P, Shrestha A A

机构信息

Department of Pediatrics, Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, Kavre, Nepal.

出版信息

Kathmandu Univ Med J (KUMJ). 2016 Apr-Jun;14(54):186-189.

Abstract

Severe gastrointestinal bleeding in newborn period is a serious but uncommon phenomenon that has a broad differential diagnosis. Primary duodenal ulcers are rare in children but stress induced ulceration in stomach occurs more often in neonatal period due to birth asphyxia, prolonged labour, cesarean deliveries, instrumentations, respiratory distress syndrome and sepsis. These present as acute onset of gastrointestinal bleeding commonly as altered gastric aspirate, hematemesis or malena. We report a case of a neonate with stress induced gastric bleeding following birth asphyxia who presented with massive gastrointestinal bleed manifesting as hematemesis and massive rectal bleeding. Resuscitation with multiple blood transfusion and parenteral use of ranitidine controlled the bleeding. Stress induced gastric ulcers should be suspected in a neonate presenting with massive gastrointestinal bleeding after difficult delivery and birth asphyxia.

摘要

新生儿期严重胃肠道出血是一种严重但不常见的现象,鉴别诊断范围广泛。原发性十二指肠溃疡在儿童中罕见,但由于出生窒息、产程延长、剖宫产、器械操作、呼吸窘迫综合征和败血症,胃应激性溃疡在新生儿期更常见。这些通常表现为胃肠道出血急性发作,常见为胃吸出物改变、呕血或黑便。我们报告一例新生儿出生窒息后发生应激性胃出血,表现为大量胃肠道出血,包括呕血和大量直肠出血。多次输血复苏及静脉使用雷尼替丁控制了出血。对于分娩困难和出生窒息后出现大量胃肠道出血的新生儿,应怀疑应激性胃溃疡。

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