Homer M J, Safaii H, Smith T J, Marchant D J
Department of Radiology, Tufts University School of Medicine, New England Medical Center Hospitals, Boston, MA.
AJR Am J Roentgenol. 1989 Dec;153(6):1187-9. doi: 10.2214/ajr.153.6.1187.
Forty consecutive cases of nonpalpable breast carcinoma presenting on the mammogram as microcalcifications without an associated mass were reviewed. The precise relationship between the mammographic microcalcification and the histologic carcinoma was determined in each case. In 25 cases (63%), the mammographic calcium was confined to the tumor, and in 13 cases (33%), the calcification was present both within the tumor and contiguous to the tumor margin. In two cases (5%), the calcium was not contained within the tumor but was located next to it. In one of these cases, the calcium was within 4 mm of the malignant neoplasm and in the other it was within 13 mm. No difference was seen between the appearance of the calcifications located within the tumor and the appearance of calcification next to the tumor. Precise histologic analysis revealed that microcalcifications that had prompted biopsy were confined to the tumor in 63%, within and contiguous to the tumor in 32%, and within 13 mm of the tumor in 5%.
回顾了40例在乳房X线照片上表现为微小钙化而无相关肿块的不可触及性乳腺癌病例。确定了每例乳房X线微小钙化与组织学癌之间的精确关系。25例（63%）中，乳房X线钙化局限于肿瘤内；13例（33%）中，钙化存在于肿瘤内及肿瘤边缘附近；2例（5%）中，钙化不在肿瘤内而是位于肿瘤旁，其中1例钙化距恶性肿瘤4毫米以内，另1例在13毫米以内。肿瘤内钙化的表现与肿瘤旁钙化的表现未见差异。精确的组织学分析显示，促使活检的微小钙化63%局限于肿瘤内，32%在肿瘤内及肿瘤边缘附近，5%在距肿瘤13毫米以内。
