Sulaiman Nada, Soon Jeanette, Park Jong Kwan, Naoum Christopher, Kueh Shaw-Hua, Blanke Philipp, Murphy Darra, Ellis Jennifer, Hague Cameron J, Leipsic Jonathon
St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.
Clin Imaging. 2017 May-Jun;43:19-23. doi: 10.1016/j.clinimag.2017.01.017. Epub 2017 Feb 2.
We sought to validate whether low dose CACS CT with hybrid IR (HIR) could replace standard dose filtered back projection (FBP).
We enrolled 100 patients to undergo low dose CACS CT with HIR, in addition to routine full dose FBP.
No significant difference between full and low dose CT in Agatston score 138.2±360.6 vs. 137.3±356.4 (p=0.272) or calcium mass score 19±48.3 vs. 18.7±49 (p=0.8), respectively. Bland-Altman analysis showed no systematic bias. Calcium volume difference was statistically significant 57.2±134 vs. 55.1±130.2 (p=0.001).
Low dose CT for calcium scoring with HIR enables stable CACS Agatston score and calcium mass quantification as compared to full dose FBP.
我们试图验证采用混合迭代重建(HIR)的低剂量冠状动脉钙化积分(CACS)CT是否可以替代标准剂量的滤波反投影(FBP)。
我们招募了100名患者,除了进行常规的全剂量FBP外,还接受采用HIR的低剂量CACS CT检查。
全剂量和低剂量CT在阿加斯顿积分方面无显著差异,分别为138.2±360.6和137.3±356.4(p = 0.272);在钙质量积分方面也无显著差异,分别为19±48.3和18.7±49(p = 0.8)。布兰德-奥特曼分析显示无系统偏差。钙体积差异具有统计学意义,分别为57.2±134和55.1±130.2(p = 0.001)。
与全剂量FBP相比,采用HIR的低剂量CT进行钙评分能够实现稳定的CACS阿加斯顿积分和钙质量定量分析。